Effect of feedback loops on the sustainability and resilience of human-ecosystems
Sign Up to like & getrecommendations! Published in 2020 at "Ecological Modelling"
DOI: 10.1016/j.ecolmodel.2020.109018
Abstract: Abstract There is a great concern about the current growing and indiscriminate human activity over the environment that supports us. Many researchers and strategists have predicted human and natural disasters based on assumptions linked to… read more here.
Keywords: system; effect feedback; target; resilience ... See more keywords
An impulsive model of endocrine regulation with two negative feedback loops
Sign Up to like & getrecommendations! Published in 2017 at "IFAC-PapersOnLine"
DOI: 10.1016/j.ifacol.2017.08.2508
Abstract: Whereas obtaining a global model of the human endocrine system remains a challenging problem, visible progress has been demonstrated in modeling its subsystems (axes) that regulate production of specific hormones. The axes are typically described… read more here.
Keywords: feedback loops; feedback; endocrine regulation; model ... See more keywords
Feedback Loops of Fire Activity and Climate Change in Canada
Sign Up to like & getrecommendations! Published in 2020 at "Eos"
DOI: 10.1029/2020eo152247
Abstract: New research documents how a warming climate contributes to patterns in wildfire severity and frequency and how the fires contribute to climate change. read more here.
Keywords: activity climate; feedback loops; fire activity; change ... See more keywords
Comprehensive Analysis of Novel lncRNA-TF Regulatory Cross Talks and Identification of Core lncRNA-TF Feedback Loops in Sarcoma.
Sign Up to like & getrecommendations! Published in 2020 at "DNA and cell biology"
DOI: 10.1089/dna.2020.5385
Abstract: Sarcomas are a broad family of cancers that arise from cells of mesenchymal origin in virtually every tissue of the body. Some transcription factors (TFs) have been reported to be involved in the pathogenesis and… read more here.
Keywords: core lncrna; topology; lncrna; cross talks ... See more keywords
LRLoop: a method to predict feedback loops in cell-cell communication
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac447
Abstract: MOTIVATION Intercellular communication (i.e. cell-cell communication) plays an essential role in multicellular organisms coordinating various biological processes. Previous studies discovered that feedback loops between two cell types are a widespread and vital signaling motif regulating… read more here.
Keywords: cell; communication; feedback loops; cell communication ... See more keywords
Coupling protocol of interlocked feedback oscillators in circadian clocks
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2020.0287
Abstract: Circadian rhythms (approx. 24 h) show the robustness of key oscillatory features such as phase, period and amplitude against external and internal variations. The robustness of Drosophila circadian clocks can be generated by interlocked transcriptional–translational… read more here.
Keywords: coupling protocol; protocol interlocked; circadian clocks; anti phase ... See more keywords
Synthesis of the Dynamical Properties of Feedback Loops in Bio-Pathways
Sign Up to like & getrecommendations! Published in 2021 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2019.2936200
Abstract: Feedback loops regulate various biological functions such as oscillations, bistability, and robustness. They play a significant role in developmental signalling and failure of feedback can lead to disease. Systematic analysis of feedback loops could be… read more here.
Keywords: synthesis dynamical; bio pathways; loops bio; feedback loops ... See more keywords
The contribution of feedback loops between miRNAs, cytokines and growth factors to the pathogenesis of psoriasis
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13520
Abstract: The present review describes in detail the existent data regarding feedback loops between miRNAs and cytokines or growth factors in the psoriatic inflammation. We have chosen to describe the roles of miR‐31, miR‐21, miR‐146a, miR‐155,… read more here.
Keywords: mirnas cytokines; growth factors; loops mirnas; cytokines growth ... See more keywords
Challenges for gatekeeping: a qualitative systems analysis of a pilot in rural China
Sign Up to like & getrecommendations! Published in 2017 at "International Journal for Equity in Health"
DOI: 10.1186/s12939-017-0593-z
Abstract: BackgroundGatekeeping involves a generalist doctor who controls patients’ access to specialist care, and has been discussed as an important policy option to rebalance the primary care and hospital sectors in low- and middle-income countries, despite… read more here.
Keywords: primary care; health; systems analysis; care ... See more keywords
Monitor to innovate with feedback loops: process evaluation protocol for an anemia prevention intervention.
Sign Up to like & getrecommendations! Published in 2022 at "Gates open research"
DOI: 10.12688/gatesopenres.13417.2
Abstract: Background: Digital process monitoring and evaluation tools designed to capture near-to-real-time intervention data paired with feedback loops have the potential to innovate intervention delivery. Objective: To describe how a multilevel social norms field trial (RANI)… read more here.
Keywords: intervention delivery; evaluation; monitor; feedback loops ... See more keywords
Complementary phase responses via functional differentiation of dual negative feedback loops
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1008774
Abstract: Multiple feedback loops are often found in gene regulations for various cellular functions. In mammalian circadian clocks, oscillations of Period1 (Per1) and Period2 (Per2) expression are caused by interacting negative feedback loops (NFLs) whose protein… read more here.
Keywords: phase; per2; phase responses; feedback loops ... See more keywords