Induction of FGFR4 by H. pylori via STAT3 with a feedforward activation loop involving SRC signaling in gastric cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.05.016
Abstract: BACKGROUND & AIMS Helicobacter pylori (H. pylori) infection is the main risk factor for gastric cancer. The role of Fibroblast Growth Factor Receptors in H. pylori-mediated gastric tumorigenesis remains largely unknown. This study investigated the… read more here.
Keywords: activation loop; fgfr4; feedforward activation; gastric cancer ... See more keywords
Feedforward activation of PRKN/parkin
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2100615
Abstract: ABSTRACT Parkinson disease is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the midbrain. The majority of early onset forms of Parkinson disease are a result of autosomal mutations in PRKN… read more here.
Keywords: activation prkn; parkinson disease; feedforward activation; prkn ... See more keywords