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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031600
Abstract: Central and peripheral serotonin (5-hydroxytryptamine, 5-HT) regulate feeding signals for energy metabolism. Disruption of central 5-HT signaling via 5-HT2C receptors (5-HT2CRs) induces leptin-independent hyperphagia in mice, leading to late-onset obesity, insulin resistance, and impaired glucose…
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Keywords:
peripheral serotonin;
central peripheral;
fgf21;
metabolic diseases ... See more keywords