Experimental and DFT simulation study of a novel felodipine cocrystal: Characterization, dissolving properties and thermal decomposition kinetics
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DOI: 10.1016/j.jpba.2018.03.006
Abstract: HIGHLIGHTSA new cocrystal of felodipine with high dissolution rate was developed.The cocrystal was characterized by XRPD, DSC, TG, IR and even DFT simulation.The cocrystal experienced different decomposition mechanism compared with intact API.DFT simulation provided theoretical… read more here.
Keywords: fel glu; thermal decomposition; dft simulation; decomposition kinetics ... See more keywords