Inhibition of bioenergetic metabolism by the combination of metformin and 2-deoxyglucose highly decreases viability of feline mammary carcinoma cells.
Sign Up to like & getrecommendations! Published in 2017 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2017.07.035
Abstract: Feline mammary carcinoma (FMC) is a highly aggressive pathology that has been proposed as an interesting model of breast cancer disease, especially for the hormone refractory subgroup. Recently, cancer cell metabolism has been described as… read more here.
Keywords: combination; metabolism; viability; mammary carcinoma ... See more keywords
TiHo-0906: a new feline mammary cancer cell line with molecular, morphological, and immunocytological characteristics of epithelial to mesenchymal transition
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-31682-1
Abstract: Feline mammary carcinomas (FMCs) with anaplastic and malignant spindle cells histologically resemble the human metaplastic breast carcinoma (hMBC), spindle-cell subtype. hMBCs display epithelial-to-mesenchymal transition (EMT) characteristics. Herein we report the establishment and characterization of a… read more here.
Keywords: tiho 0906; epithelial mesenchymal; cell line; feline mammary ... See more keywords
The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89894-x
Abstract: Feline mammary carcinoma (FMC) shows great similarities to human breast cancer in the cellular and molecular levels. So, in cats as in humans, the role of immune responses is indicated to detect and follow up… read more here.
Keywords: carcinoma; treatment; mammary carcinoma; feline mammary ... See more keywords
Properties of the feline tumour suppressor reduced expression in immortalized cells (REIC/Dkk-3).
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary and comparative oncology"
DOI: 10.1111/vco.12254
Abstract: Reduced expression in immortalized cells (REIC/Dkk-3), a member of the human Dickkopf (Dkk) family, is a growth suppressor in human and canine mammary tumours. Mammary gland tumours are common neoplasms with high malignancy in female… read more here.
Keywords: expression; feline mammary; reic dkk; suppressor ... See more keywords
Neutrophil-to-Lymphocyte ratio (NLR) is an independent prognostic marker for feline mammary carcinomas.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary and comparative oncology"
DOI: 10.1111/vco.12686
Abstract: Blood leukocyte counts and respective derived ratios have been described as potential prognostic markers in several tumours in veterinary oncology. This study aimed to evaluate peripheral blood leukocyte subpopulations and NLR as prognostic factors for… read more here.
Keywords: nlr independent; mammary carcinomas; independent prognostic; feline mammary ... See more keywords
Consensus for the diagnosis, prognosis and treatment of feline mammary tumors
Sign Up to like & getrecommendations! Published in 2018 at "Brazilian Journal of Veterinary Research and Animal Science"
DOI: 10.11606/issn.1678-4456.bjvras.2018.135084
Abstract: Mammary neoplasms are described as the third most common type of feline tumor, after haematopoietic and skin tumors, and present a challenge for clinicians because the prognosis for feline mammary tumors ranges from guarded to… read more here.
Keywords: prognosis treatment; mammary tumors; treatment feline; feline mammary ... See more keywords
HER2 Amplification Status in Feline Mammary Carcinoma: A Tissue Microarray–Fluorescence In Situ Hydridization–Based Study
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary Pathology"
DOI: 10.1177/0300985818808531
Abstract: Human epidermal growth factor receptor 2 (HER2) is a tyrosine kinase receptor overexpressed in a subset of breast cancer due to HER2 gene amplification. HER2 protein is expressed in feline mammary carcinomas, but little is… read more here.
Keywords: mammary carcinomas; her2; feline mammary; amplification ... See more keywords
Histologic evaluation of Ki-67 and cleaved caspase-3 expression in feline mammary carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Feline Medicine and Surgery"
DOI: 10.1177/1098612x16634150
Abstract: Objectives The purpose of this study was to evaluate histopathologic aspects of, and the expression of Ki-67 and cleaved caspase-3 in, feline mammary carcinoma (FMC). Methods Feline mammary tumors were surgically obtained by mastectomy from… read more here.
Keywords: caspase expression; mammary carcinoma; feline mammary; cleaved caspase ... See more keywords