Tri-block co-polymer nanocarriers for enhancement of oral delivery of felodipine: preparation, in vitro characterization and ex vivo permeation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Liposome Research"
DOI: 10.1080/08982104.2017.1327541
Abstract: Abstract This study aimed to prepare, optimize and characterize novel felodipine-loaded polymeric nanomicelles, using a pluronic mixture of F127 and P123. Thin-film hydration method was adopted for the preparation of different polymeric nanomicelles (T1–T12) according… read more here.
Keywords: felodipine; oral delivery; permeation; polymer ... See more keywords
Dry Gel Containing Optimized Felodipine-Loaded Transferosomes: a Promising Transdermal Delivery System to Enhance Drug Bioavailability
Sign Up to like & getrecommendations! Published in 2018 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-018-1020-5
Abstract: Felodipine has a very low bioavailability due to first-pass metabolism. The aim of this study was to enhance its bioavailability by transdermal application. Felodipine-loaded transferosomes were prepared by thin-film hydration using different formulation variables. An… read more here.
Keywords: felodipine; formula; bioavailability; gel ... See more keywords
Development of Simple Dissolution Methods for Felodipine and Combined Amlodipine Besylate -Indapamide Extended Release Tablets without Stationary (Felodipine) Basket.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220526122615
Abstract: BACKGROUND The dissolution method for certain drugs needs specialized conditions. Dissolution testing for felodipine extended release (ER) tablets (Plendil® 5mg) and amlodipine-indapamide fixed dose (Natrilam®, 5/1.5 mg) ER tablets require the use of a stationary… read more here.
Keywords: extended release; dissolution; felodipine basket; felodipine ... See more keywords
Impact of 14 types of genetic polymorphisms on antihypertensive efficacy of felodipine in healthy Chinese subjects .
Sign Up to like & getrecommendations! Published in 2020 at "International journal of clinical pharmacology and therapeutics"
DOI: 10.5414/cp203686
Abstract: OBJECTIVE This study evaluated different influences of 14 single nucleotide polymorphisms (SNPs) and demographic factors leading to individual differences in the antihypertensive efficacy of felodipine in healthy Chinese subjects. MATERIALS AND METHODS 24 subjects were… read more here.
Keywords: felodipine healthy; healthy chinese; chinese subjects; felodipine ... See more keywords