Undernutrition and hyperandrogenism during pregnancy: Role in programming of cardiovascular disease and infertility
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23239
Abstract: Maternal nutritional status programs the development of several systems in female offspring, with effects that depend on the severity, duration, and window of development when the nutritional perturbation is imposed. On the basis of the… read more here.
Keywords: pregnancy; hyperandrogenism; disease; undernutrition ... See more keywords
Maternal exposure to perfluorooctanoic acid (PFOA) causes liver toxicity through PPAR-α pathway and lowered histone acetylation in female offspring mice
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-019-05258-z
Abstract: The study was conducted to investigate the liver toxicity in female offspring mice induced by maternal exposure to perfluorooctanoic acid (PFOA). Fifty pregnant Kunming mice were randomly divided into 5 groups with 10 of each,… read more here.
Keywords: liver toxicity; pfoa; offspring mice; maternal exposure ... See more keywords
Maternal Perinatal Exposure to Dibutyl Phthalate Promotes Ovarian Dysfunction in Adult Female Offspring via Downregulation of TGF-β2 and TGF-β3
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00785-y
Abstract: Maternal exposure to dibutyl phthalate (DBP) may result in ovarian dysfunction in female offspring. However, the underlying mechanisms remain elusive. Pregnant Sprague–Dawley rats were intraperitoneally injected with different doses of DBP, estradiol, and corn oil… read more here.
Keywords: tgf tgf; adult female; tgf; female offspring ... See more keywords
Placental Treatment Improves Cardiac Tolerance to Ischemia/Reperfusion Insult in Adult Male and Female Offspring Exposed to Prenatal Hypoxia.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105461
Abstract: Offspring born from complicated pregnancies are at greater risk of cardiovascular disease in adulthood. Prenatal hypoxia is a common pregnancy complication that results in placental oxidative stress and impairs fetal development. Adult offspring exposed to… read more here.
Keywords: adult; cardiac tolerance; tolerance; male female ... See more keywords
Maternal exposure to Δ9-tetrahydrocannabinol impairs female offspring glucose homeostasis and endocrine pancreatic development in the rat.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2020.04.070
Abstract: Recent reports indicate that 7% of pregnant mothers in North America use cannabis. This is concerning given that in utero exposure to Δ9-tetrahydrocannabinol (Δ9-THC), the main psychoactive component in cannabis, causes fetal growth restriction and… read more here.
Keywords: glucose homeostasis; exposure; thc; maternal exposure ... See more keywords
Adverse reproductive function induced by maternal BPA exposure is associated with abnormal autophagy and activating inflamation via mTOR and TLR4/NF-κB signaling pathways in female offspring rats.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2020.07.001
Abstract: Bisphenol A (BPA) can affect reproductive function, but its mechanism of reproductive toxicity is unclear, and the effect of BPA on the onset of puberty was inconsistent. The main purpose of this study is to… read more here.
Keywords: bpa; exposure; mtor; reproductive function ... See more keywords
Articular damages in multi-generational female offspring due to prenatal caffeine exposure correlates with H3K9 deacetylation of TGFβ signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology"
DOI: 10.1016/j.tox.2020.152533
Abstract: dverse environment during pregnancy could lead to maternal glucocorticoid overexposure in utero, and then induce the intrauterine growth retardation (IUGR) and the programmed change in cartilage development. The transforming growth factor β (TGFβ) signaling pathway… read more here.
Keywords: caffeine; signaling pathway; female offspring; tgf signaling ... See more keywords
Attenuated Tregs increase susceptibility to type 1 diabetes in prenatal nicotine exposed female offspring mice.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.08.016
Abstract: The recession of regulatory T cells (Tregs) is pivotal for type 1 diabetes (T1D) progressing. Our previous study observed the decreased Tregs in prenatal nicotine exposure (PNE) offspring, but whether this led to the onset… read more here.
Keywords: pne; female offspring; type diabetes; prenatal nicotine ... See more keywords
Thermoneutrality effects on developmental programming of obesity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174422000502
Abstract: Abstract Developmental programming studies using mouse models have housed the animals at human thermoneutral temperatures (22°C) which imposes constant cold stress. As this impacts energy homeostasis, we investigated the effects of two housing temperatures (22°C… read more here.
Keywords: thermoneutrality effects; libitum diet; thermoneutrality; temperature ... See more keywords
Colonic Bacteroides are positively associated with trabecular bone structure and programmed by maternal vitamin D in male but not female offspring in an obesogenic environment
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Obesity"
DOI: 10.1038/ijo.2017.294
Abstract: Background/Objectives:The gut microbiota is determined early in life, possibly including pregnancy. Pioneering data suggest vitamin D, a nutrient important for bone health, affects this microbiota. We found that high maternal vitamin D lowered circulating lipopolysaccharide… read more here.
Keywords: male female; bone; structure; vitamin ... See more keywords
Interspecific interference in the closely related predatory mites Neoseiulus womersleyi and Neoseiulus longispinosus (Acari: Phytoseiidae)
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Acarology"
DOI: 10.1080/01647954.2017.1293732
Abstract: ABSTRACT Reproductive interference is known to occur in the morphologically similar species Neoseiulus womersleyi and Neoseiulus longispinosus: crosses between N. longispinosus females and N. womersleyi males produce (a few) female offspring, reciprocal crosses produce only… read more here.
Keywords: interference; neoseiulus longispinosus; longispinosus; neoseiulus womersleyi ... See more keywords