Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases.
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DOI: 10.1038/s41593-021-01001-5
Abstract: Multiple studies indicate that adult male rodents perform better than females on spatial problems and have a lower threshold for long-term potentiation (LTP) of hippocampal CA3-to-CA1 synapses. We report here that, in rodents, prepubescent females… read more here.
Keywords: female rodents; prepubescent female; ltp; hippocampal ltp ... See more keywords