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   Articles with "female sheep" as a keyword



Developmental programming: Adipose depot-specific changes and thermogenic adipocyte distribution in the female sheep

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recommendations! Published in 2020 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2019.110691

Abstract: Prenatal testosterone (T)-treated female sheep exhibit an enhanced inflammatory and oxidative stress state in the visceral adipose tissue (VAT) but not in the subcutaneous (SAT), while surprisingly maintaining insulin sensitivity in both depots. In adult… read more here.

Keywords: adipocyte; female sheep; depot specific; distribution ... See more keywords

GENDER-RELATED VARIATIONS IN PATHOPHYSIOLOGICAL RESPONSES TO METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS PNEUMONIA AND SEPSIS

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recommendations! Published in 2023 at "Shock"

DOI: 10.1097/shk.0000000000002108

Abstract: ABSTRACT In preclinical studies, the protective effects of female sex hormones and the immunosuppressive effects of male sex hormones were demonstrated. However, gender-related differences in multiorgan failure and mortality in clinical trials have not been… read more here.

Keywords: sepsis; time; methicillin resistant; female sheep ... See more keywords

Effect of Gender on the Pharmacokinetics of Meloxicam in Sheep

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recommendations! Published in 2025 at "Journal of Veterinary Pharmacology and Therapeutics"

DOI: 10.1111/jvp.70005

Abstract: The objective of this investigation was to ascertain the impact of gender on the pharmacokinetics of meloxicam in sheep. The research was carried out on six female and six male Romanov sheep. Meloxicam was administered… read more here.

Keywords: gender pharmacokinetics; gender; female sheep; pharmacokinetics meloxicam ... See more keywords

Developmental Programming: Prenatal Testosterone Excess on Liver and Muscle Coding and Non-Coding RNA in Female Sheep.

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recommendations! Published in 2021 at "Endocrinology"

DOI: 10.1210/endocr/bqab225

Abstract: Prenatal testosterone (T)-treated female sheep manifest peripheral insulin resistance, ectopic lipid accumulation and insulin signaling disruption in liver and muscle. This study investigated transcriptional changes and transcriptome signature of prenatal T excess-induced hepatic and muscle-specific… read more here.

Keywords: muscle; liver muscle; female sheep; prenatal testosterone ... See more keywords

The air pollutant phenanthrene disrupts calcium cycling and alters repolarization in female sheep ventricular cardiomyocytes

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recommendations! Published in 2025 at "Physiological Reports"

DOI: 10.14814/phy2.70471

Abstract: Multiple epidemiological studies link cardiac dysfunction with increased levels of air pollution. While cellular mechanisms underlying such dysfunction are yet to be fully elucidated, a proposed mediator of this effect is phenanthrene, a 3‐ringed polycyclic… read more here.

Keywords: phenanthrene; calcium transient; air pollutant; ventricular myocytes ... See more keywords