Developmental programming: Adipose depot-specific changes and thermogenic adipocyte distribution in the female sheep
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2019.110691
Abstract: Prenatal testosterone (T)-treated female sheep exhibit an enhanced inflammatory and oxidative stress state in the visceral adipose tissue (VAT) but not in the subcutaneous (SAT), while surprisingly maintaining insulin sensitivity in both depots. In adult… read more here.
Keywords: adipocyte; female sheep; depot specific; distribution ... See more keywords
GENDER-RELATED VARIATIONS IN PATHOPHYSIOLOGICAL RESPONSES TO METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS PNEUMONIA AND SEPSIS
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DOI: 10.1097/shk.0000000000002108
Abstract: ABSTRACT In preclinical studies, the protective effects of female sex hormones and the immunosuppressive effects of male sex hormones were demonstrated. However, gender-related differences in multiorgan failure and mortality in clinical trials have not been… read more here.
Keywords: sepsis; time; methicillin resistant; female sheep ... See more keywords
Developmental Programming: Prenatal Testosterone Excess on Liver and Muscle Coding and Non-Coding RNA in Female Sheep.
Sign Up to like & getrecommendations! Published in 2021 at "Endocrinology"
DOI: 10.1210/endocr/bqab225
Abstract: Prenatal testosterone (T)-treated female sheep manifest peripheral insulin resistance, ectopic lipid accumulation and insulin signaling disruption in liver and muscle. This study investigated transcriptional changes and transcriptome signature of prenatal T excess-induced hepatic and muscle-specific… read more here.
Keywords: muscle; liver muscle; female sheep; prenatal testosterone ... See more keywords