The metabolic fate of fenclozic acid in chimeric mice with a humanized liver
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DOI: 10.1007/s00204-018-2274-0
Abstract: The metabolic fate of the human hepatotoxin fenclozic acid ([2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid) (Myalex) was studied in normal and bile-cannulated chimeric mice with a humanized liver, following oral administration of 10 mg/kg. This in vivo animal model was… read more here.
Keywords: mice humanized; chimeric mice; fenclozic acid; acid ... See more keywords