LncRNA‐FENDRR mediates VEGFA to promote the apoptosis of brain microvascular endothelial cells via regulating miR‐126 in mice with hypertensive intracerebral hemorrhage
Sign Up to like & getrecommendations! Published in 2018 at "Microcirculation"
DOI: 10.1111/micc.12499
Abstract: LncRNA‐FENDRR is a kind of endothelial genes critical for vascular development. Moreover, miR‐126 and vascular endothelial growth factor A (VEGFA) are also involved in the physiological process of vascular endothelial cells. This study aimed to… read more here.
Keywords: mir 126; intracerebral hemorrhage; hypertensive intracerebral; lncrna fendrr ... See more keywords
FENDRR suppresses cervical cancer proliferation and invasion by targeting miR-15a/b-5p and regulating TUBA1A expression
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01223-w
Abstract: Background Previous literature has revealed long non-coding RNAs (lncRNAs) are crucial regulators for cell functions and gene expression. LncRNA fetal-lethal non-coding developmental regulatory RNA (FENDRR) was reported as a biological suppressor in several types of… read more here.
Keywords: tuba1a; mir 15a; cervical cancer; expression ... See more keywords
The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Oncotarget"
DOI: 10.18632/oncotarget.22154
Abstract: It is increasingly evident that non-coding RNAs play a significant role in tumour development. However, we still have a limited knowledge of the clinical significance of long non-coding RNAs (lncRNAs) in lung cancer. The FENDRR… read more here.
Keywords: expression; lung; fendrr foxf1; fendrr ... See more keywords
Long non-coding RNA FENDRR inhibits cell proliferation and is associated with good prognosis in breast cancer
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DOI: 10.2147/ott.s149511
Abstract: Introduction FENDRR is a long non-coding RNA (lncRNA) that mediates the modification of the epigenetic landscape of target promoters by binding to polycomb repressive complex 2. However, the role of FENDRR in breast cancer remains… read more here.
Keywords: cancer; cell proliferation; fendrr; breast cancer ... See more keywords
LncRNA FENDRR in Carcinoma-Associated Fibroblasts Regulates the Angiogenesis of Oral Squamous Cell Carcinoma Through the PI3K/AKT Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.616576
Abstract: Angiogenesis is essential for the development of tumors. Studies have shown that carcinoma-associated fibroblasts (CAFs) are involved in regulating tumor angiogenesis, but the mechanism remains unclear. Recently, long noncoding RNAs (lncRNAs) have been proved to… read more here.
Keywords: carcinoma; angiogenesis; pi3k akt; fendrr ... See more keywords
The FENDRR/FOXC2 Axis Contributes to Multidrug Resistance in Gastric Cancer and Correlates With Poor Prognosis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.634579
Abstract: The dysregulation of long non-coding RNAs (lncRNAs) and transcription factors (TFs) is closely related to the development and progression of drug resistance in cancer chemotherapy. However, their regulatory interactions in the multidrug resistance (MDR) of… read more here.
Keywords: poor prognosis; fendrr foxc2; resistance; foxc2 ... See more keywords
Prognostic and Predicted Significance of FENDRR in Colon and Rectum Adenocarcinoma
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DOI: 10.3389/fonc.2021.668595
Abstract: Background The role of fetal-lethal non-coding developmental regulatory RNA (FENDRR) has been explored in various cancers; however, its relationship with colon adenocarcinoma/rectum adenocarcinoma (COAD/READ) remains unclear. The objectives of this study were to identify and… read more here.
Keywords: coad read; fendrr; rectum adenocarcinoma; fendrr expression ... See more keywords
Association of the Genetic Variation in the Long Non-Coding RNA FENDRR with the Risk of Developing Hypertrophic Cardiomyopathy
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DOI: 10.3390/life12060818
Abstract: Background: In around 40–60% of Hypertrophic Cardiomyopathy (HCM) cases pathogenic variants are not identified. Our aim was to evaluate the possible association of lncRNAs with the risk of developing HCM. Methods: We sequenced 10 lncRNAs… read more here.
Keywords: hypertrophic cardiomyopathy; risk developing; hcm; fendrr ... See more keywords