Increasing fengycin production by strengthening the fatty acid synthesis pathway and optimizing fermentation conditions
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2021.108235
Abstract: Abstract In the present work, Bacillus subtilis 168 was engineered as a cell factory for fengycin production by activating its dormant native fengycin synthetase. Initially, the sfp gene from Bacillus amyloliquefaciens FZB42 was introduced into… read more here.
Keywords: production; fengycin production; increase; synthesis ... See more keywords
Improved Production of Fengycin in Bacillus subtilis by Integrated Strain Engineering Strategy.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00380
Abstract: Fengycin is a lipopeptide with broad-spectrum antifungal activity. However, its low yield limits its commercial application. Therefore, we iteratively edited multiple target genes associated with fengycin synthesis by combinatorial metabolic engineering. The ability of Bacillus… read more here.
Keywords: bacillus subtilis; integrated strain; strain engineering; production ... See more keywords