Metabolic engineering of Corynebacterium glutamicum for the fermentative production of halogenated tryptophan.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2018.12.008
Abstract: Halogenated compounds, like 7-chloro-l-tryptophan, are important intermediates or components of bioactive substances relevant for the pharmaceutical, chemical and agrochemical industries. About 20% of all pharmaceutical small molecule drugs and around 30% of all active compounds… read more here.
Keywords: production; metabolic engineering; tryptophan; glutamicum ... See more keywords
Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b00981
Abstract: Three rosmarinic acid analogs produced by recombinant Escherichia coli, two xanthones from fungi and honokiol from plants, were explored as the substrates of E. coli harboring a glucosyltransferase mutant UGT73B6FS to generate phenolic glucosides. Six… read more here.
Keywords: glucosides escherichia; production phenolic; escherichia coli; glucosyltransferase ... See more keywords
Fermentative Production of Melanin by Auricularia auricula
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Food Processing and Preservation"
DOI: 10.1111/jfpp.12909
Abstract: Low cost fermentation medium using wheat bran extract as a major nutrient source, was evaluated for production of melanin from the fungus Auricularia auricula in submerged culture. Effects of wheat bran extract, l-tyrosine and CuSO4… read more here.
Keywords: production; melanin; wheat bran; production melanin ... See more keywords
Fermentative Production of N-Alkylated Glycine Derivatives by Recombinant Corynebacterium glutamicum Using a Mutant of Imine Reductase DpkA From Pseudomonas putida
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2019.00232
Abstract: Sarcosine, an N-methylated amino acid, shows potential as antipsychotic, and serves as building block for peptide-based drugs, and acts as detergent when acetylated. N-methylated amino acids are mainly produced chemically or by biocatalysis, with either… read more here.
Keywords: dpka; production; sarcosine; fermentative production ... See more keywords
Fermentative Production of l-2-Hydroxyglutarate by Engineered Corynebacterium glutamicum via Pathway Extension of l-Lysine Biosynthesis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.630476
Abstract: l-2-hydroxyglutarate (l-2HG) is a trifunctional building block and highly attractive for the chemical and pharmaceutical industries. The natural l-lysine biosynthesis pathway of the amino acid producer Corynebacterium glutamicum was extended for the fermentative production of… read more here.
Keywords: production; lysine biosynthesis; hydroxyglutarate; fermentative production ... See more keywords