Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.08.014
Abstract: ABSTRACT Ferritin nanocages are of particular interest as a novel platform for drug and vaccine delivery, diagnosis, biomineralization scaffold and more, due to their perfect and complex symmetry, ideal physical properties, high biocompatibility, low toxicity… read more here.
Keywords: ferritin; tumor targeting; half life; ferritin nanocages ... See more keywords
Engineered ferritin nanocages as natural contrast agents in magnetic resonance imaging
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra05681h
Abstract: We report the development of a self-assembling protein nanocage as a contrast agent for magnetic resonance imaging (MRI). The protein nanocage is derived from genetically engineered ferritin from Archaeoglobus fulgidus (AfFtnAA). Iron (Fe) was loaded… read more here.
Keywords: resonance imaging; contrast; engineered ferritin; magnetic resonance ... See more keywords
Protein-Based Nanoparticles for the Imaging and Treatment of Solid Tumors: The Case of Ferritin Nanocages, a Narrative Review
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13122000
Abstract: Protein nanocages have been studied extensively, due to their unique architecture, exceptional biocompatibility and highly customization capabilities. In particular, ferritin nanocages (FNs) have been employed for the delivery of a vast array of molecules, ranging… read more here.
Keywords: review; treatment solid; solid tumors; imaging treatment ... See more keywords