Structure‐based design of ferritin nanoparticle immunogens displaying antigenic loops of Neisseria gonorrhoeae
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12267
Abstract: Effective vaccines are urgently needed to combat gonorrhea, a common sexually transmitted bacterial infection, for which treatment options are diminishing due to rapid emergence of antibiotic resistance. We have used a rational approach to the… read more here.
Keywords: neisseria gonorrhoeae; ferritin nanoparticle; antigenic peptides; structure ... See more keywords
Engineered Ferritin Nanoparticle Vaccines Enable Rapid Screening of Antibody Functionalisation to Boost Immune Responses.
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DOI: 10.1002/adhm.202202595
Abstract: Employing monoclonal antibodies to target vaccine antigens to different immune cells within lymph nodes where adaptive immunity is initiated can provide a mechanism to fine tune the magnitude of quality of immune responses. However, studying… read more here.
Keywords: engineered ferritin; ferritin nanoparticle; immune responses; rapid screening ... See more keywords
A ferritin nanoparticle vaccine for foot-and-mouth disease virus elicited partial protection in mice.
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DOI: 10.1016/j.vaccine.2020.06.063
Abstract: Foot-and-mouth disease (FMD) is an acute, febrile, and highly contagious infectious disease common in cloven-hoofed animals. Outbreaks and epidemics of FMD can result in major economic losses of livestock. Using ferritin nanoparticles as the scaffold… read more here.
Keywords: ferritin nanoparticle; foot mouth; nanoparticle; mouth disease ... See more keywords
A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine Is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model
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DOI: 10.3390/vaccines10050717
Abstract: The COVID-19 pandemic has had a staggering impact on social, economic, and public health systems worldwide. Vaccine development and mobilization against SARS-CoV-2 (the etiologic agent of COVID-19) has been rapid. However, novel strategies are still… read more here.
Keywords: covid model; ferritin nanoparticle; cynomolgus macaque; covid ... See more keywords