2D MoS2 Nanosheets Induce Ferroptosis by Promoting NCOA4-Dependent Ferritinophagy and Inhibiting Ferroportin.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202208063
Abstract: The exposure of MoS2 nanosheets can cause cytotoxicity, which causes health risks and affects its medical applications. However, knowledge of the underlying molecular mechanisms remains limited. This study reports that MoS2 nanosheets induces ferroptosis in… read more here.
Keywords: ferritinophagy; nanosheets induce; mos2 nanosheets; ncoa4 dependent ... See more keywords
The critical role of ferritinophagy in human disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.933732
Abstract: Ferritinophagy is a type of autophagy mediated by nuclear receptor activator 4 (NCOA4), which plays a role in inducing ferroptosis by regulating iron homeostasis and producing reactive oxygen species in cells. Under physiological conditions, ferritinophagy… read more here.
Keywords: iron; ferritinophagy; role ferritinophagy; ferroptosis ... See more keywords