TRIM11 suppresses ferritinophagy and gemcitabine sensitivity through UBE2N/TAX1BP1 signaling in pancreatic ductal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30346
Abstract: Gemcitabine is first‐line chemotherapy for pancreatic cancer, however, the development of resistance limits its effectiveness. The tripartite motif‐containing 11 (TRIM11) protein plays crucial roles in tumor development and undergoes auto‐polyubiquitination to promote interactions in selective… read more here.
Keywords: trim11; ferritinophagy gemcitabine; ube2n tax1bp1; pancreatic ductal ... See more keywords