A novobiocin derivative, XN4, triggers ferroptosis in gastric cancer cells via the activation of NOX4
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DOI: 10.1080/13880209.2022.2099431
Abstract: Abstract Context A novobiocin derivative, XN4, has been shown to promote cell apoptosis in chronic myeloid leukaemia. Objective This study explores the mechanism by which XN4 promotes ferroptosis of gastric cancer (GC) cells. Materials and… read more here.
Keywords: xn4; novobiocin derivative; ferroptosis gastric; gastric cancer ... See more keywords
LTBP2 Knockdown Promotes Ferroptosis in Gastric Cancer Cells through p62-Keap1-Nrf2 Pathway
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DOI: 10.1155/2022/6532253
Abstract: Gastric cancer (GC) is one of the most common gastrointestinal malignancies. Ferroptosis is a new type of peroxidation-driven and iron-dependent cell death. However, the biological functions and exact regulatory mechanisms of ferroptosis in GC remain… read more here.
Keywords: keap1 nrf2; p62 keap1; ferroptosis gastric; gastric cancer ... See more keywords
Comprehensive Analysis of the Aberrance and Functional Significance of Ferroptosis in Gastric Cancer
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DOI: 10.3389/fphar.2022.919490
Abstract: Objective: Ferroptosis is a type of iron-dependent necrosis related to cancer. Nevertheless, the features of ferroptosis in gastric cancer (GC) remain poorly understood. This study conducted a systematic analysis of ferroptosis regulators in GC. Methods:… read more here.
Keywords: ferroptosis regulators; analysis; ferroptosis gastric; gastric cancer ... See more keywords
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination
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DOI: 10.7150/ijbs.69454
Abstract: Ferroptosis is a novel form of cell death that is closely associated with the formation of many tumors. Our study focused on the mechanism by which long noncoding RNAs (lncRNAs) regulate ferroptosis in gastric cancer… read more here.
Keywords: bdnf; fbxw7; ferroptosis gastric; vdac3 ubiquitination ... See more keywords