A double-edged sword with a therapeutic target: iron and ferroptosis in immune regulation.
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition reviews"
DOI: 10.1093/nutrit/nuac071
Abstract: Cellular activities such as DNA synthesis, adenosine triphosphate production, and mitochondrial respiration are affected by iron metabolism. Disturbance of iron homeostasis usually leads to damage in cells and organs in the context of iron overload… read more here.
Keywords: immune regulation; iron; ferroptosis immune; iron ferroptosis ... See more keywords
Identification of Markers for Diagnosis and Treatment of Diabetic Kidney Disease Based on the Ferroptosis and Immune
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DOI: 10.1155/2022/9957172
Abstract: Background In advanced diabetic kidney disease (DKD), iron metabolism and immune dysregulation are abnormal, but the correlation is not clear. Therefore, we aim to explore the potential mechanism of ferroptosis-related genes in DKD and their… read more here.
Keywords: ferroptosis immune; kidney disease; diabetic kidney; gene ... See more keywords
Establishment of a prognostic ferroptosis- and immune-related long noncoding RNAs profile in kidney renal clear cell carcinoma
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DOI: 10.3389/fgene.2022.915372
Abstract: Background: Ferroptosis and immunity are novel treatments that target several cancers, including kidney renal clear cell carcinoma (KIRC). Long noncoding RNAs (lncRNAs) are an important class of gene expression regulators that play fundamental roles in… read more here.
Keywords: ferroptosis immune; immune related; kidney renal; ferroptosis ... See more keywords
Prognostic Signatures Based on Ferroptosis- and Immune-Related Genes for Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma
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DOI: 10.3389/fonc.2021.774558
Abstract: Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) are among the most common malignancies of the female genital tract. Ferroptosis and immunity regulate each other and play important roles in the progression of CESC. The… read more here.
Keywords: ferroptosis immune; immune related; prognostic signatures; cervical squamous ... See more keywords
Combination Analysis of Ferroptosis and Immune Status Predicts Patients Survival in Breast Invasive Ductal Carcinoma
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DOI: 10.3390/biom13010147
Abstract: Ferroptosis is a new form of iron-dependent cell death and plays an important role during the occurrence and development of various tumors. Increasingly, evidence shows a convincing interaction between ferroptosis and tumor immunity, which affects… read more here.
Keywords: immune status; breast invasive; ferroptosis immune; immune ... See more keywords