Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs.
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DOI: 10.1016/j.canlet.2020.02.015
Abstract: Ferroptosis, a form of regulated cell death, is initiated by oxidative perturbations of the intracellular microenvironment, which is under the constitutive control of glutathione peroxidase 4 (GPX4). Ferrous iron (Fe2+) accumulation and lipid peroxidation are… read more here.
Keywords: novel pharmacological; mechanism anti; ferroptosis; ferroptosis novel ... See more keywords
Ferroptosis as a Novel Therapeutic Target for Diabetes and Its Complications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.853822
Abstract: The global diabetes epidemic and its complications are increasing, thereby posing a major threat to public health. A comprehensive understanding of diabetes mellitus (DM) and its complications is necessary for the development of effective treatments.… read more here.
Keywords: novel therapeutic; therapeutic target; ferroptosis novel; ferroptosis ... See more keywords
Ferroptosis—A Novel Mechanism With Multifaceted Actions on Stroke
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.881809
Abstract: As a neurological disease with high morbidity, disability, and mortality, the pathological mechanism underlying stroke involves complex processes such as neuroinflammation, oxidative stress, apoptosis, autophagy, and excitotoxicity; but the related research on these molecular mechanisms… read more here.
Keywords: ferroptosis novel; mechanism multifaceted; novel mechanism; mechanism ... See more keywords
Ferroptosis: A novel therapeutic strategy and mechanism of action in glioma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.947530
Abstract: Glioma is the most common malignant tumor of the central nervous system and resistance is easily developed to chemotherapy drugs during the treatment process, resulting in high mortality and short survival in glioma patients. Novel… read more here.
Keywords: novel therapeutic; therapeutic strategy; ferroptosis novel; glioma ... See more keywords