Ferroptosis and its potential as a therapeutic target.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114486
Abstract: Ferroptosis is a recently defined form of programmed cell death that is different from apoptosis. It is an iron-dependent programmed cell death and the accumulation of lipid hydroperoxides to lethal levels make ferroptosis distinct. Ferroptosis… read more here.
Keywords: target; ferroptosis; potential therapeutic; ferroptosis potential ... See more keywords
Ferroptosis as a potential new therapeutic target for diabetes and its complications
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine Connections"
DOI: 10.1530/ec-22-0419
Abstract: Diabetes is a complex metabolic disease. In recent years, diabetes and its chronic complications have become a health hotspot of global concern. It is very important to find promising therapeutic targets and directions. Ferroptosis is… read more here.
Keywords: potential new; new therapeutic; therapeutic target; ferroptosis potential ... See more keywords
Ferroptosis and Its Potential Role in the Nervous System Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s351799
Abstract: Abstract Ferroptosis is a novel regulated cell death characterized by metabolic disorders and iron-dependent oxidative destruction of the lipid bilayer. It is primarily caused by the imbalance of oxidation and anti-oxidation in the body and… read more here.
Keywords: potential role; nervous system; ferroptosis potential; ferroptosis ... See more keywords
Ferroptosis Is a Potential Novel Diagnostic and Therapeutic Target for Patients With Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.649045
Abstract: Cardiomyocyte death is a fundamental progress in cardiomyopathy. However, the mechanism of triggering the death of myocardial cells remains unclear. Ferroptosis, which is the nonapoptotic, iron-dependent, and peroxidation-driven programmed cell death pathway, that is abundant… read more here.
Keywords: potential novel; novel diagnostic; diagnostic therapeutic; ferroptosis ... See more keywords
Emerging Mechanisms and Disease Implications of Ferroptosis: Potential Applications of Natural Products
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.774957
Abstract: Ferroptosis, a newly discovered form of regulatory cell death (RCD), has been demonstrated to be distinct from other types of RCD, such as apoptosis, necroptosis, and autophagy. Ferroptosis is characterized by iron-dependent lipid peroxidation and… read more here.
Keywords: implications ferroptosis; emerging mechanisms; ferroptosis potential; disease implications ... See more keywords
Ferroptosis: A Potential Target in Cardiovascular Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.813668
Abstract: Ferroptosis is a new form of regulatory cell death characterized by iron-dependent and intracellular lipid peroxidation. Ferroptosis can be divided into two stages. The first stage is iron overload in the cell, which generates a… read more here.
Keywords: ferroptosis; cardiovascular disease; ferroptosis potential; potential target ... See more keywords
Ferroptosis: A potential opportunity for intervention of pre-metastatic niche
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.980620
Abstract: It is widely thought that the tumor microenvironment (TME) provides the “soil” for malignant tumors to survive. Prior to metastasis, the interaction at the host site between factors secreted by primary tumors, bone-marrow-derived cells, with… read more here.
Keywords: potential opportunity; pre metastatic; ferroptosis potential; metastatic niche ... See more keywords
Autophagy-dependent ferroptosis as a potential treatment for glioblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1091118
Abstract: Glioblastoma (GBM) is the most common malignant primary brain tumor with a poor 5-year survival rate. Autophagy is a conserved intracellular degradation system that plays a dual role in GBM pathogenesis and therapy. On one… read more here.
Keywords: autophagy dependent; glioblastoma; potential treatment; ferroptosis potential ... See more keywords
Ferroptosis: A Potential Therapeutic Target in Acute Kidney Injury
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23126583
Abstract: Ferroptosis is a recently recognized form of nonapoptotic cell death that is triggered by reactive oxidative species (ROS) due to iron overload, lipid peroxidation accumulation, or the inhibition of phospholipid hydroperoxidase glutathione peroxidase 4 (GPX4).… read more here.
Keywords: acute kidney; kidney injury; ferroptosis potential; injury ... See more keywords
Ferroptosis as a Potential Therapeutic Target of Traditional Chinese Medicine for Mycotoxicosis: A Review
Sign Up to like & getrecommendations! Published in 2023 at "Toxics"
DOI: 10.3390/toxics11040395
Abstract: Mycotoxin contamination has become one of the biggest hidden dangers of food safety, which seriously threatens human health. Understanding the mechanisms by which mycotoxins exert toxicity is key to detoxification. Ferroptosis is an adjustable cell… read more here.
Keywords: potential therapeutic; ferroptosis potential; mycotoxicosis; chinese herbal ... See more keywords