Abstract 6143: Novel multiplexed assays of ferroptosis, pyroptosis and necroptosis biomarkers for translational studies
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DOI: 10.1158/1538-7445.am2023-6143
Abstract: Background: The recent discovery that multiple chemo- and immuno-therapies activate non-apoptotic cell death pathways such as necroptosis, pyroptosis, and ferroptosis in cancer cells has necessitated development of pharmacodynamic biomarker assays to study their novel mechanisms… read more here.
Keywords: pyroptosis necroptosis; ferroptosis; cancer; ferroptosis pyroptosis ... See more keywords
Combination of ferroptosis and pyroptosis to construct a prognostic classifier and predict immune landscape, chemotherapeutic efficacy and immunosuppressive molecules in hepatocellular carcinoma
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DOI: 10.1186/s12885-022-09301-0
Abstract: Background The induction of ferroptosis and pyroptosis has been highlighted as a novel approach to decide cancer cell fate. However, few studies have systematically explored the role of combining these two novel cell death modalities… read more here.
Keywords: ferroptosis; hepatocellular carcinoma; immunosuppressive molecules; ferroptosis pyroptosis ... See more keywords
Cytoglobin Silencing Promotes Melanoma Malignancy but Sensitizes for Ferroptosis and Pyroptosis Therapy Response
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DOI: 10.3390/antiox11081548
Abstract: Despite recent advances in melanoma treatment, there are still patients that either do not respond or develop resistance. This unresponsiveness and/or acquired resistance to therapy could be explained by the fact that some melanoma cells… read more here.
Keywords: cygb; ferroptosis pyroptosis; sensitivity; therapy ... See more keywords