FerrDb V2: update of the manually curated database of ferroptosis regulators and ferroptosis-disease associations
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac935
Abstract: Abstract Ferroptosis is a mode of regulated cell death characterized by iron-dependent accumulation of lipid peroxidation. It is closely linked to the pathophysiological processes in many diseases. Since our publication of the first ferroptosis database… read more here.
Keywords: ferroptosis regulators; disease associations; ferroptosis disease; ferroptosis ... See more keywords
Cross-talk between cuproptosis and ferroptosis regulators defines the tumor microenvironment for the prediction of prognosis and therapies in lung adenocarcinoma
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DOI: 10.3389/fimmu.2022.1029092
Abstract: Cuproptosis, a newly identified form of programmed cell death, plays vital roles in tumorigenesis. However, the interconnectivity of cuproptosis and ferroptosis is poorly understood. In our study, we explored genomic alterations in 1162 lung adenocarcinoma… read more here.
Keywords: cuproptosis; lung adenocarcinoma; ferroptosis regulators; cross talk ... See more keywords
Comprehensive Analysis of the Aberrance and Functional Significance of Ferroptosis in Gastric Cancer
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DOI: 10.3389/fphar.2022.919490
Abstract: Objective: Ferroptosis is a type of iron-dependent necrosis related to cancer. Nevertheless, the features of ferroptosis in gastric cancer (GC) remain poorly understood. This study conducted a systematic analysis of ferroptosis regulators in GC. Methods:… read more here.
Keywords: ferroptosis regulators; analysis; ferroptosis gastric; gastric cancer ... See more keywords
Integrative analysis of the molecular mechanisms, immunological features and immunotherapy response of ferroptosis regulators across 33 cancer types
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DOI: 10.7150/ijbs.64654
Abstract: Ferroptosis is a recently described mode of cell death caused by the accumulation of intracellular iron and lipid reactive oxygen species (ROS), which play critical roles in tumorigenesis and cancer progression. However, the underlying molecular… read more here.
Keywords: ferroptosis regulators; regulators across; molecular mechanisms; cancer types ... See more keywords