TRIB2 desensitizes ferroptosis via βTrCP-mediated TFRC ubiquitiantion in liver cancer cells
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00574-1
Abstract: Tribbles homolog 2 (TRIB2) is known to boost liver tumorigenesis via regulating Ubiquitin (Ub) proteasome system (UPS). At least two ways are involved, i.e., acts as an adaptor protein to modulate ubiquitination functions of certain… read more here.
Keywords: ferroptosis; trcp; liver cancer; trib2 ... See more keywords
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Liver International"
DOI: 10.1111/liv.15459
Abstract: Rifampicin is the most common pathogenic factor in anti‐tuberculosis drug‐induced liver injury (AT‐DILI), the mechanisms that it promotes hepatocyte damage in AT‐DILI are not yet to be thoroughly elucidated. In this study, we investigated the… read more here.
Keywords: inhibition hspa8; ferroptosis via; hspa8 rifampicin; rifampicin contributes ... See more keywords