Self-assembled thioether-bridged paclitaxel-dihydroartemisinin prodrug for amplified antitumor efficacy-based cancer ferroptotic-chemotherapy.
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DOI: 10.1039/d2bm02032g
Abstract: Ferroptosis has been proposed as one form of iron-dependent cell death, overgeneration of high-toxicity hydroxyl radicals (˙OH) tumor sites via Fenton reactions induced cell membrane damage. However, the insufficient intracellular concentrations of both iron and… read more here.
Keywords: ferroptotic chemotherapy; prodrug; paclitaxel; cancer ... See more keywords