Articles with "ferroptotic pathway" as a keyword



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Tryptophan Metabolism Acts as a New Antiā€Ferroptotic Pathway to Mediate Tumor Growth

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Published in 2023 at "Advanced Science"

DOI: 10.1002/advs.202204006

Abstract: Emerging evidence reveals that amino acid metabolism plays an important role in ferroptotic cell death. The conversion of methionine to cysteine is well known to protect tumour cells from ferroptosis upon cysteine starvation through transamination.… read more here.

Keywords: metabolism; ferroptotic pathway; new anti; tryptophan metabolism ... See more keywords
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Extracellular vesicles from endothelial progenitor cells prevent steroid-induced osteoporosis by suppressing the ferroptotic pathway in mouse osteoblasts based on bioinformatics evidence

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-52513-x

Abstract: Abnormal antioxidative capabilities were observed in the pathogenesis of steroid-induced osteoporosis (SIOP). Ferroptosis is a recently discovered type of cell death that is characterized by the overproduction of ROS in response to GPX4 and system… read more here.

Keywords: ferroptotic pathway; epc evs; steroid induced; bone ... See more keywords