Ferumoxytol Nanoparticles Target Biofilms Causing Tooth Decay in the Human Mouth.
Sign Up to like & getrecommendations! Published in 2021 at "Nano letters"
DOI: 10.1021/acs.nanolett.1c02702
Abstract: Severe tooth decay has been associated with iron deficiency anemia that disproportionally burdens susceptible populations. Current modalities are insufficient in severe cases where pathogenic dental biofilms rapidly accumulate, requiring new antibiofilm approaches. Here, we show… read more here.
Keywords: ferumoxytol nanoparticles; causing tooth; target biofilms; tooth decay ... See more keywords
Topical ferumoxytol nanoparticles disrupt biofilms and prevent tooth decay in vivo via intrinsic catalytic activity
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-05342-x
Abstract: Ferumoxytol is a nanoparticle formulation approved by the U.S. Food and Drug Administration for systemic use to treat iron deficiency. Here, we show that, in addition, ferumoxytol disrupts intractable oral biofilms and prevents tooth decay… read more here.
Keywords: ferumoxytol nanoparticles; tooth decay; ferumoxytol; topical ferumoxytol ... See more keywords