Toxic effects of maternal exposure to silver nanoparticles on mice fetal development during pregnancy.
Sign Up to like & getrecommendations! Published in 2019 at "Birth defects research"
DOI: 10.1002/bdr2.1605
Abstract: BACKGROUND Silver nanoparticles (SNPs) are being increasingly used in medical and industrial products. The aim of the present study was to evaluate the toxic effect of maternal exposure to SNP (1 mg/kg/day, 70 nm) on fetal… read more here.
Keywords: silver nanoparticles; pregnancy; fetal development; maternal exposure ... See more keywords
Maternal genetic disorders and fetal development
Sign Up to like & getrecommendations! Published in 2020 at "Prenatal Diagnosis"
DOI: 10.1002/pd.5659
Abstract: With improvements in early diagnosis and management of genetic diseases, more women with genetic disorders are reaching reproductive age and becoming pregnant. While pregnancy can have a significant impact on a woman's health when there… read more here.
Keywords: genetic disorders; maternal genetic; fetal development; disorders fetal ... See more keywords
Prenatal development of the human tympanic ring: a morphometric study with clinical correlations
Sign Up to like & getrecommendations! Published in 2021 at "Surgical and Radiologic Anatomy"
DOI: 10.1007/s00276-020-02654-w
Abstract: To establish normal reference values for the human Tympanic Ring (TR) during prenatal development, and to describe and interpret its growth dynamics. Fifty spontaneously aborted human fetuses aged 12–37 weeks with normal external characteristics were… read more here.
Keywords: human tympanic; tympanic ring; prenatal development; fetal development ... See more keywords
Embryonic and fetal development of the collared peccary (Pecari tajacu).
Sign Up to like & getrecommendations! Published in 2019 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2019.106123
Abstract: The relative timing of the main fetal development events in species determine the extent of fetal development at birth, which range along a gradient of having altricial and precocial traits. The results from this study… read more here.
Keywords: tdl; peccary pecari; collared peccary; fetal development ... See more keywords
Adverse effects of prenatal dexamethasone exposure on fetal development
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Reproductive Immunology"
DOI: 10.1016/j.jri.2022.103619
Abstract: Dexamethasone has been widely used in clinical practice to promote fetal lung maturity and reduce neonatal respiratory distress syndrome and perinatal mortality. Nevertheless, its administration is a double-edged sword, as a large number of studies… read more here.
Keywords: dexamethasone exposure; fetal development; prenatal dexamethasone; dexamethasone ... See more keywords
Satellite rats are redundant in embryo-fetal development studies.
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2017.06.042
Abstract: Routinely in many laboratories, satellite rats are added to embryo-fetal development (EFD) studies for pharmaceuticals to assess toxicokinetic (TK) properties, because it is assumed that collection of multiple blood samples with relatively large volumes might… read more here.
Keywords: blood sampling; satellite rats; embryo fetal; fetal development ... See more keywords
A shortened study design for embryo-fetal development studies in the minipig.
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2018.06.009
Abstract: The minipig is accepted from scientific and regulatory perspectives for the safety evaluation of drug candidates on embryo-fetal development. The relative size and the duration of gestation (112-115 days) in the minipig is, however, considered… read more here.
Keywords: study design; fetal development; embryo fetal; shortened study ... See more keywords
A multi-institutional study benchmarking the zebrafish developmental assay for prediction of embryotoxic plasma concentrations from rat embryo-fetal development studies.
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2019.02.004
Abstract: Predicting embryotoxicity of pharmaceutical compounds or industrial chemicals is crucial for public safety. Conventional studies which monitor embryo-fetal development in rats and rabbits are costly and time consuming. Alternative assays which are simpler and less… read more here.
Keywords: plasma; plasma concentrations; embryo fetal; assay ... See more keywords
Embryonic and fetal development of the red brocket deer (Mazama americana).
Sign Up to like & getrecommendations! Published in 2019 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2019.05.015
Abstract: The red brocket deer (Mazama americana), a medium-sized Neotropical ungulate, is one of the most hunted mammals in the Amazon. This study analyzes the intrauterine development in the red brocket deer through the description of… read more here.
Keywords: red brocket; development; fetal development; brocket deer ... See more keywords
An atlas of dynamic chromatin landscapes in mouse fetal development
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2093-3
Abstract: The Encyclopedia of DNA Elements (ENCODE) project has established a genomic resource for mammalian development, profiling a diverse panel of mouse tissues at 8 developmental stages from 10.5 days after conception until birth, including transcriptomes,… read more here.
Keywords: chromatin; state accessibility; development; fetal development ... See more keywords
Spatiotemporal DNA methylome dynamics of the developing mouse fetus
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2119-x
Abstract: Cytosine DNA methylation is essential for mammalian development but understanding of its spatiotemporal distribution in the developing embryo remains limited1,2. Here, as part of the mouse Encyclopedia of DNA Elements (ENCODE) project, we profiled 168… read more here.
Keywords: methylation; dna; developmental stages; fetal development ... See more keywords