Embryo‐fetal developmental toxicity and toxicokinetics of loxoprofen tromethamine intravenously administered to pregnant rats
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DOI: 10.1002/bdr2.2116
Abstract: Loxoprofen tromethamine is a novel structural compound related to loxoprofen. It has been used for the treatment of pain and inflammation. However, the embryo‐fetal developmental toxicity (EFDT) of loxoprofen tromethamine has not been evaluated in… read more here.
Keywords: developmental toxicity; fetal developmental; embryo fetal; toxicokinetics loxoprofen ... See more keywords
Review of embryo-fetal developmental toxicity studies performed for pharmaceuticals approved by FDA in 2016 and 2017.
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DOI: 10.1016/j.reprotox.2018.04.008
Abstract: Details of embryo-fetal development (EFD) studies were compiled for all FDA drug approvals in 2016-17. Rats and rabbits were used for 63% of small molecule (SM) drugs. The cynomolgus monkey was used for 47% of… read more here.
Keywords: cancer drugs; fetal developmental; review embryo; embryo fetal ... See more keywords
MRI for Fetal Developmental Brain Abnormalities: Perspectives From the Pregnant Patient
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DOI: 10.1177/1049732318764390
Abstract: Ultrasound is routinely used as a prenatal screening and diagnostic tool but has limitations. Some anomalies in the developing fetal brain can be difficult to detect, and in utero magnetic resonance imaging (iuMRI) is increasingly… read more here.
Keywords: brain abnormalities; developmental brain; fetal developmental; mri fetal ... See more keywords