Simulated confined placental mosaicism proportion (SCPMP) based on cell-free fetal DNA fraction enrichment can reduce false-positive results in non-invasive prenatal testing.
Sign Up to like & getrecommendations! Published in 2022 at "Prenatal diagnosis"
DOI: 10.1002/pd.6150
Abstract: OBJECTIVE To decrease the false-positive rate of NIPT using cell-free fetal DNA (cffDNA) fraction enrichment and the simulated confined placental mosaicism proportion (SCPMP) threshold application via cffDNA quantification. METHOD Using a cffDNA enrichment method, 303… read more here.
Keywords: free fetal; cell free; enrichment; false positive ... See more keywords
Presence of fetal DNA in maternal exhaled breath condensate
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DOI: 10.1002/pd.6277
Abstract: Cell‐free DNA has been found in all body fluids, but DNAs emerging from locations that are not in direct contact with breath in exhaled breath condensate (EBC) are yet to be found. The potential of… read more here.
Keywords: dna; breath; fetal dna; breath condensate ... See more keywords
Content of Free Fetal DNA in Maternal Blood and Expression of DNA Recognition Receptors ZBP-1 in Placental Tissue in Preeclampsia and Preterm Labor
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04665-z
Abstract: We evaluated the content of cell-free fetal DNA in maternal blood and expression of ZBP-1 receptors in the placental tissue of women with uncomplicated pregnancy, preeclampsia, and preterm labor. The study included 16 women with… read more here.
Keywords: free fetal; dna; preterm labor; preeclampsia ... See more keywords
Evolution of Down Syndrome Prenatal Screening Clinical Practices in Québec.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC"
DOI: 10.1016/j.jogc.2019.09.025
Abstract: OBJECTIVE Prenatal screening for Down syndrome (DS) has evolved greatly over the last decades with the improvement of first- and second-trimester serum screening and the introduction of cell-free fetal DNA. This study aimed to estimate… read more here.
Keywords: prenatal screening; free fetal; 2005 2007; diagnosis ... See more keywords
Maternal Serum sEndoglin and Cell-Free Fetal DNA as Probable Markers of Preeclampsia: A Study in Single Center, Egypt
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DOI: 10.1080/08820139.2019.1578790
Abstract: ABSTRACT Background: This study was conducted to compare the levels of maternal serum soluble endoglin (sEng) and cell-free fetal DNA (cffDNA) in pregnant females with PE to normotensive pregnant ones, together with relating these levels… read more here.
Keywords: free fetal; study; maternal serum; cell free ... See more keywords
Validation of fetal microchimerism after pregnancy in the ovine using qPCR.
Sign Up to like & getrecommendations! Published in 2021 at "Translational animal science"
DOI: 10.1093/tas/txab100
Abstract: Fetal microchimerism has been detected in maternal tissues of humans and rodents during and after pregnancy. Studies focusing on fetal DNA transfer to maternal tissues in domestic animals are limited, especially in sheep. Fetal ram… read more here.
Keywords: dna; male; fetal microchimerism; soft tissues ... See more keywords
Vox Sanguinis International Forum on application of fetal blood grouping: summary
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DOI: 10.1111/vox.12616
Abstract: Cloning of blood group genes and subsequent elucidation of the molecular backgrounds to blood group polymorphisms have made it possible to predict blood group phenotypes from the DNA of a patient or donor, when a… read more here.
Keywords: blood group; fetus; dna; fetal dna ... See more keywords
Prenatal Diagnosis of β-thalassemia with Cell-free Fetal DNA in Maternal Plasma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the College of Physicians and Surgeons--Pakistan : JCPSP"
DOI: 10.29271/jcpsp.2019.05.483
Abstract: The aim of this study was to explore the feasibility of non-invasive prenatal genetic diagnosis of β-thalassemia with small fragments of cell-free fetal DNA (cffDNA) in peripheral blood of pregnant women. It was an observational… read more here.
Keywords: free fetal; diagnosis; cell free; fetal dna ... See more keywords
Applying amplification refractory mutation system technique to detecting cell-free fetal DNA for single-gene disorders purpose
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1071406
Abstract: Non-invasive prenatal diagnosis for single-gene disorders (NIPD) is still in development and deserves further study. The advent of next-generation sequencing technology significantly improved the detection of multiple mutations for non-invasive prenatal diagnosis for single-gene disorder… read more here.
Keywords: dna; gene disorders; fetal dna; technique ... See more keywords
Fetal DNA Causes Sex-Specific Inflammation From Human Fetal Membranes
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DOI: 10.3389/fphys.2022.901726
Abstract: Inflammation is central to the mechanisms of parturition, but the lack of understanding of how it is controlled in normal parturition hampers our ability to understand how it may diverge resulting in preterm birth. Cell-free… read more here.
Keywords: inflammation; dna; human fetal; fetal membranes ... See more keywords
Cell-Free Fetal DNA and Non-Invasive Prenatal Diagnosis of Chromosomopathies and Pediatric Monogenic Diseases: A Critical Appraisal and Medicolegal Remarks
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13010001
Abstract: Cell-free fetal DNA (cffDNA) analysis is a non-invasive prenatal diagnostic test with a fundamental role for the screening of chromosomic or monogenic pathologies of the fetus. Its administration is performed by fetal DNA detection in… read more here.
Keywords: dna; non invasive; cell free; invasive prenatal ... See more keywords