Prediction of fetal hemoglobin after multiple intrauterine transfusions: 419
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2018.11.440
Abstract: circulation. We sought to evaluate changes in the pulmonary artery doppler following maternal hyperoxygenation in utero, during the third trimester of pregnancy. STUDY DESIGN: Forty six women with a singleton gestation greater than or equal… read more here.
Keywords: following maternal; maternal hyperoxygenation; hyperoxygenation; prediction fetal ... See more keywords
Fetal hemoglobin levels in premature newborns. Should we reconsider transfusion of adult donor blood?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2021.04.018
Abstract: PURPOSE The aim of this study was to assess the percent decrease in fetal hemoglobin (HbF) after transfusion of adult-derived donor packed red blood cell (pRBC) units in extremely low gestational age newborns (ELGANs). METHODS… read more here.
Keywords: hbf; hemoglobin; blood; fetal hemoglobin ... See more keywords
A hypothesis about the role of fetal hemoglobin in COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2020.109994
Abstract: COVID-19 infection is less common in children (with higher fetal hemoglobin levels). In our preliminary study, we also observed a low prevalence and fatality of COVID-19 in countries with high rate of hemoglobinopathy carries. Given… read more here.
Keywords: hypothesis role; hemoglobin; role fetal; fetal hemoglobin ... See more keywords
The role of hemoglobin degradation pathway in preeclampsia: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.01.014
Abstract: INTRODUCTION Overproduction of fetal hemoglobin by the placenta leading to increased consumption of endogenous heme scavenging proteins has been recently implicated as a novel pathway in the pathogenesis of preeclampsia. The aim of the present… read more here.
Keywords: hemoglobin; systematic review; preeclampsia; fetal hemoglobin ... See more keywords
Unusual stability exhibited by (AT)XN12(AT)Y motif associated with high fetal hemoglobin levels
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2018.1532320
Abstract: Abstract Quasi-palindromic sequences (AT)XN12(AT)Y present in HS2 (hypersensitive site 2) of the human β-globin locus are known to be significantly associated with increased fetal hemoglobin (HbF) levels. High HbF levels in some adults arise due… read more here.
Keywords: xn12; hbf; fetal hemoglobin; unusual stability ... See more keywords
The state of the art of fetal hemoglobin-inducing agents
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2022.2141708
Abstract: ABSTRACT Introduction Sickle cell anemia (SCA) is a hematological genetic disorder caused by a mutation in the gene of the β-globin. Pharmacological treatments will continue to be an important approach, including the strategy to induce… read more here.
Keywords: new drugs; art fetal; hbf; state art ... See more keywords
Heterogeneity of fetal hemoglobin production in adult red blood cells.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in hematology"
DOI: 10.1097/moh.0000000000000640
Abstract: PURPOSE OF REVIEW Small amounts of fetal hemoglobin can be expressed in a subset of adult red blood cells called F-cells. This review examines the potential mechanisms and clinical implications of the heterogeneity of fetal… read more here.
Keywords: fetal hemoglobin; blood cells; hemoglobin; adult red ... See more keywords
Mutation Screening of the Krüppel-like Factor 1 Gene in Individuals With Increased Fetal Hemoglobin Referred for Hemoglobinopathy Investigation in South of Iran
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001093
Abstract: Background: Any mutation in the Krüppel-like factor 1 (KLF1) gene may interfere with its proper related function in the erythropoiesis process and lead to alterations in proper activation of its downstream protein through globin switching,… read more here.
Keywords: hbf; individuals increased; fetal hemoglobin; gene ... See more keywords
Improved Fetal Hemoglobin With mTOR Inhibitor–Based Immunosuppression in a Kidney Transplant Recipient With Sickle Cell Disease
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Transplantation"
DOI: 10.1111/ajt.14263
Abstract: Fetal hemoglobin induction is a key point in the management of sickle cell disease (SCD). We report the case of a kidney transplant recipient with SCD who was treated with everolimus, a mammalian target of… read more here.
Keywords: hemoglobin; transplant recipient; kidney transplant; cell disease ... See more keywords
Biclonal evolution of chronic lymphocytic leukaemia
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Haematology"
DOI: 10.1111/bjh.17543
Abstract: et al. Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania. BMC Med Genet. 2020;21:125. 12. Xu J, Bauer DE, Kerenyi MA, Vo TD, Hou S,… read more here.
Keywords: fetal hemoglobin; biclonal evolution; lymphocytic leukaemia; evolution chronic ... See more keywords
Manipulation of Developmental Gamma-Globin Gene Expression: an Approach for Healing Hemoglobinopathies
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00253-20
Abstract: β-Hemoglobinopathies are the most common monogenic disorders, and a century of research has provided us with a better understanding of the attributes of these diseases. Allogenic stem cell transplantation was the only potentially curative option… read more here.
Keywords: fetal hemoglobin; hemoglobin; gamma globin; gene ... See more keywords