Experimental models of maternal–fetal interface and their potential use for nanotechnology applications
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11222
Abstract: During pregnancy, the placenta regulates the transfer of oxygen, nutrients, and residual products between the maternal and fetal bloodstreams and is a key determinant of fetal exposure to xenobiotics from the mother. To study the… read more here.
Keywords: experimental models; interface potential; maternal fetal; nanotechnology ... See more keywords
Pregnancy and spontaneous fetal loss: A pig perspective
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22847
Abstract: Pigs have a unique, non‐invasive epitheliochorial placenta where maternal and fetal layers lay in apposition. Indentation of fetal capillaries into the trophoblasts and maternal capillaries into the uterine epithelium reduce the distance between the fetal… read more here.
Keywords: fetal loss; pregnancy; spontaneous fetal; maternal fetal ... See more keywords
Extracellular vesicles in host-pathogen interactions and immune regulation — exosomes as emerging actors in the immunological theater of pregnancy
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e02355
Abstract: This review correlates and summarizes the role of the maternal-fetal interface in the immune tolerance of the fetus and the processes that lead to infection avoidance, emphasizing the participation of exosomes and other extracellular vesicles… read more here.
Keywords: extracellular vesicles; pathogen; pregnancy; maternal fetal ... See more keywords
Destruction in maternal-fetal interface of URSA patients via the increase of the HMGB1-RAGE/TLR2/TLR4-NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117543
Abstract: AIMS HMGB1 has been reported to play a crucial role in the physiological and pathophysiological responses during pregnancy. However, it is still unknown whether excessively expressed HMGB1 at the maternal-fetal interface related to Unexplained Recurrent… read more here.
Keywords: hmgb1; tlr2 tlr4; rage tlr2; maternal fetal ... See more keywords
Characterization of C-C motif chemokine ligand 4 in the porcine endometrium during the presence of the maternal-fetal interface.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.06.022
Abstract: Chemokines and their receptors play a crucial role in embryo implantation at the maternal-fetal interface during pregnancy. In this study, we investigated the role of CCL4 in development of the porcine endometrium in the early… read more here.
Keywords: porcine endometrium; ple cells; porcine; ccl4 ... See more keywords
Unique maternal immune and functional microbial profiles during prenatal stress
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-77265-x
Abstract: Maternal stress during pregnancy is widespread and is associated with poor offspring outcomes, including long-term mental health issues. Prenatal stress-induced fetal neuroinflammation is thought to underlie aberrant neurodevelopment and to derive from a disruption in… read more here.
Keywords: prenatal stress; maternal immune; unique maternal; stress ... See more keywords
Uterine NK cell functions at maternal-fetal interface
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac094
Abstract: Abstract During pregnancy, maternal decidual tissue interacts with fetal trophoblasts. They constitute the maternal-fetal interface responsible for supplying nutrition to the fetus. Uterine natural killer (uNK) cells are the most abundant immune cells at the… read more here.
Keywords: cell; fetal interface; maternal fetal; pregnancy ... See more keywords
Single-cell characterization of trophoblast-epithelial interactions at the human maternal-fetal interface during early implantation.
Sign Up to like & getrecommendations! Published in 2025 at "Biology of reproduction"
DOI: 10.1093/biolre/ioaf246
Abstract: Human embryo implantation is crucial for successful pregnancy, yet its molecular mechanisms remain poorly understood due to ethical and technological limitations. In this study, we constructed an embryo implantation model using Single-cell RNA Sequencing (scRNA-seq)… read more here.
Keywords: tep; fetal interface; implantation; maternal fetal ... See more keywords
Kisspeptin prevents pregnancy loss by modulating the immune microenvironment at the maternal‐fetal interface in recurrent spontaneous abortion
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13818
Abstract: Immune factors are crucial in the development of recurrent spontaneous abortion (RSA). This study aimed to investigate whether kisspeptin regulates immune cells at the maternal‐fetal interface and whether G protein‐coupled receptor 54 (GPR54) is involved… read more here.
Keywords: spontaneous abortion; recurrent spontaneous; maternal fetal; fetal interface ... See more keywords
The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0230295
Abstract: The new type of pneumonia caused by the SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) has been declared as a global public health concern by WHO. As of April 3, 2020, more than 1,000,000 human… read more here.
Keywords: study; maternal fetal; sars cov; cell ... See more keywords
3D model of the maternal-fetal interface: challenges, recent advances and beyond.
Sign Up to like & getrecommendations! Published in 2023 at "Histology and histopathology"
DOI: 10.14670/hh-18-584
Abstract: Embryo implantation is a complex and highly coordinated process that involves an intricate network of factors establishing intimate contact at the maternal-fetal interface. Knowledge of the human implantation process is compromised by both ethical issues,… read more here.
Keywords: interface challenges; fetal interface; maternal fetal; model maternal ... See more keywords