Tetramethyl bisphenol A stimulates proliferation but inhibits fetal Leydig cell function in male rats by targeting estrogen receptor α after in utero exposure
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23633
Abstract: Tetramethyl bisphenol A (TMBPA) is a widely used flame retardant. TMBPA has been a toxic to Leydig cells in puberty, but it remains unclear whether TMBPA has a similar inhibitor effect on fetal Leydig cells… read more here.
Keywords: utero exposure; leydig; fetal leydig; tmbpa ... See more keywords
In utero single low-dose exposure of cadmium induces rat fetal Leydig cell dysfunction.
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DOI: 10.1016/j.chemosphere.2017.11.159
Abstract: Cadmium chloride (Cd) is a potent endocrine disruptor and may cause the malformation in the male reproductive tract. However, the effects of a single in utero exposure to low doses of Cd on fetal Leydig… read more here.
Keywords: leydig cell; rat fetal; fetal leydig; exposure ... See more keywords
Leydig progenitor cells in fetal testis
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DOI: 10.1016/j.mce.2016.12.006
Abstract: Testicular Leydig cells play pivotal roles in masculinization of organisms by producing androgens. At least two distinct Leydig cell populations sequentially emerge in the mammalian testis. Leydig cells in the fetal testis (fetal Leydig cells)… read more here.
Keywords: testis; fetal leydig; adult leydig; leydig ... See more keywords
In utero combined di-(2-ethylhexyl) phthalate and diethyl phthalate exposure cumulatively impairs rat fetal Leydig cell development.
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DOI: 10.1016/j.tox.2018.01.002
Abstract: Phthalate diesters, including di-(2-ethylhexyl) phthalate (DEHP) and diethyl phthalate (DEP), are chemicals to which humans are ubiquitously exposed. Humans are exposed simultaneously to multiple environmental chemicals, including DEHP and DEP. There is little information available… read more here.
Keywords: leydig cell; fetal leydig; phthalate; cell ... See more keywords
Effects of bis(2-butoxyethyl) phthalate exposure in utero on the development of fetal Leydig cells in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.08.008
Abstract: Phthalates are plasticizers widely found in the environment. They are potential endocrine disruptors. Bis(2-butoxyethyl) phthalate (BBOP) is a unique phthalate that contains oxygen atoms in the carbon backbone. Little is known about its reproductive and… read more here.
Keywords: fetal leydig; phthalate; exposure; bbop ... See more keywords