In an in‐vitro model using human fetal membranes, 17‐&agr; hydroxyprogesterone caproate is not an optimal progestogen for inhibition of fetal membrane weakening
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2017.10.004
Abstract: Background The progestogen 17‐&agr; hydroxyprogesterone caproate (17‐OHPC) is 1 of only 2 agents recommended for clinical use in the prevention of spontaneous preterm delivery, and studies of its efficacy have been conflicting. We have developed… read more here.
Keywords: fetal membrane; hydroxyprogesterone caproate; factor; membrane weakening ... See more keywords
Fetal membrane exosome profiling in vitro reveals distinct pathways induced by infection and inflammation: 102
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DOI: 10.1016/j.ajog.2018.11.113
Abstract: 102 Fetal membrane exosome profiling in vitro reveals distinct pathways induced by infection and inflammation Luis A. Monsivais, Samantha Sheller-Miller, Rheanna Urrabaz-Garza, George Saade, Christopher L. Dixon, Ramkumar Menon The University of Texas Medical Branch,… read more here.
Keywords: exosome profiling; membrane exosome; fetal membrane; profiling vitro ... See more keywords
Miniaturized Bioengineered Models for Preterm Fetal Membrane Healing
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DOI: 10.1159/000525559
Abstract: Introduction: The reason for the absence of fetal membrane (FM) healing after a fetoscopic intervention is still unknown. We hypothesize that the lack of robust miniaturized models to study preterm FM functions is currently hampering… read more here.
Keywords: fetal membrane; membrane healing; migration; miniaturized bioengineered ... See more keywords
In vivo Sealing of Fetoscopy-Induced Fetal Membrane Defects by Mussel Glue
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DOI: 10.1159/000528473
Abstract: Introduction: The benefits of fetal surgery are impaired by the high incidence of iatrogenic preterm prelabor rupture of the fetal membranes (iPPROM), for which chorioamniotic separation has been suggested as a potential initiator. Despite the… read more here.
Keywords: mussel glue; tissue response; fetal membrane; vivo sealing ... See more keywords
Formalin-Fixed Paraffin-Embedded (FFPE) samples are not a beneficial replacement for frozen tissues in fetal membrane microbiota research
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DOI: 10.1371/journal.pone.0265441
Abstract: Formalin-Fixed Paraffin-Embedded (FFPE) tissues are routinely collected, archived, and used for clinical diagnosis, including maternal and neonatal health. Applying FFPE samples to microbiota research would be beneficial to reduce preparation, storage and costs associated with… read more here.
Keywords: membrane; fetal membrane; membrane samples; ffpe samples ... See more keywords
The Role of Danger Associated Molecular Patterns in Human Fetal Membrane Weakening
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DOI: 10.3389/fphys.2020.00602
Abstract: The idea that cellular stress (including that precipitated by stretch), plays a significant role in the mechanisms initiating parturition, has gained considerable traction over the last decade. One key consequence of this cellular stress is… read more here.
Keywords: associated molecular; human fetal; fetal membrane; molecular patterns ... See more keywords
Healing Mechanism of Ruptured Fetal Membrane
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DOI: 10.3389/fphys.2020.00623
Abstract: Preterm premature rupture of membranes (pPROM) typically leads to spontaneous preterm birth within several days. In a few rare cases, however, amniotic fluid leakage ceases, amniotic fluid volume is restored, and pregnancy continues until term.… read more here.
Keywords: healing mechanism; fetal membrane; ruptured fetal; amnion ... See more keywords
Interleukin (IL)-6: A Friend or Foe of Pregnancy and Parturition? Evidence From Functional Studies in Fetal Membrane Cells
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DOI: 10.3389/fphys.2020.00891
Abstract: Objective Protection of the fetus within the amniotic sac is primarily attained by remodeling fetal membrane (amniochorion) cells through cyclic epithelial to mesenchymal and mesenchymal to epithelial (EMT and MET) transitions. Endocrine and paracrine factors… read more here.
Keywords: membrane cells; pregnancy; inflammation; fetal membrane ... See more keywords
Calcium, Potassium, Sodium, and Magnesium Concentrations in the Placenta, Umbilical Cord, and Fetal Membrane from Women with Multiple Pregnancies
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DOI: 10.3390/life13010153
Abstract: Calcium (Ca), potassium (K), sodium (Na), and magnesium (Mg) are the elements responsible for the fundamental metabolic and biochemical processes in the cells of the body. The demand for these elements increases significantly during pregnancy,… read more here.
Keywords: multiple pregnancies; fetal membrane; umbilical cord; membrane ... See more keywords