Fetal programming as a predictor of adult health or disease: the need to reevaluate fetal heart function
Sign Up to like & getrecommendations! Published in 2017 at "Heart Failure Reviews"
DOI: 10.1007/s10741-017-9638-z
Abstract: Epidemiologic and experimental evidence suggests that adverse stimuli during critical periods in utero permanently alters organ structure and function and may have persistent consequences for the long-term health of the offspring. Fetal hypoxia, maternal malnutrition,… read more here.
Keywords: fetal programming; heart; physiology; function ... See more keywords
Insights into sympathetic nervous system and GPCR interplay in fetal programming of hypertension: a bridge for new pharmacological strategies.
Sign Up to like & getrecommendations! Published in 2020 at "Drug discovery today"
DOI: 10.1016/j.drudis.2020.01.019
Abstract: Cardiovascular diseases (CVDs) are the most common cause of death from noncommunicable diseases worldwide. In addition to the classical CVD risk factors related to lifestyle and/or genetic background, exposure to an adverse intrauterine environment compromises… read more here.
Keywords: fetal programming; nervous system; sympathetic nervous; programming hypertension ... See more keywords
The close link between the fetal programming imprinting and neurodegeneration in adulthood: The key role of “hemogenic endothelium” programming
Sign Up to like & getrecommendations! Published in 2021 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2021.111461
Abstract: The research on neurodegenerative diseases (NeuroDegD) has been traditionally focused on later life stages. There is now an increasing evidence, that they may be programmed during early development. Here, we propose that NeuroDegD are the… read more here.
Keywords: programming; fetal programming; role; hemogenic endothelium ... See more keywords
Advanced neuroimaging: A window into the neural correlates of fetal programming related to prenatal exposure to maternal depression and SSRIs.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in perinatology"
DOI: 10.1016/j.semperi.2020.151223
Abstract: Fetal programming is a conceptual framework whereby the in utero environment shapes the offspring's neurodevelopment. Maternal depression and treatment with selective serotonin reuptake inhibitor (SSRI) antidepressants during pregnancy are common prenatal exposures that affect critical… read more here.
Keywords: fetal programming; depression; maternal depression; exposure ... See more keywords
Vascular angiotensin AT1 receptor neuromodulation in fetal programming of hypertension.
Sign Up to like & getrecommendations! Published in 2019 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2018.10.003
Abstract: Fetal stress increases the susceptibility to cardiovascular diseases in adult age, including hypertension, a process known as fetal programming of hypertension (FPH). This study intends to investigate the interplay between vascular sympathetic nervous system (SNS)… read more here.
Keywords: fetal programming; programming hypertension; at1; hypertension ... See more keywords
Fetal programming of neuropsychiatric disorders by maternal pregnancy depression: a systematic mini review
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Research"
DOI: 10.1038/s41390-018-0173-y
Abstract: BackgroundMaternal depression complicates a large proportion of pregnancies. Current evidence shows numerous harmful effects on the offspring. Reviews, which include depression, concluded that stress has harmful effects on the offspring’s outcomes neuro-cognitive development, temperament traits,… read more here.
Keywords: mini review; fetal programming; depression; pregnancy ... See more keywords
Fetal programming and the angiotensin-(1-7) axis: a review of the experimental and clinical data.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical science"
DOI: 10.1042/cs20171550
Abstract: Hypertension is the primary risk factor for cardiovascular disease that constitutes a serious worldwide health concern and a significant healthcare burden. As the majority of hypertension has an unknown etiology, considerable research efforts in both… read more here.
Keywords: axis; programming; hypertension; fetal programming ... See more keywords
Facts and hypotheses about the programming of neuroplastic deficits by prenatal malnutrition
Sign Up to like & getrecommendations! Published in 2019 at "Nutrition Reviews"
DOI: 10.1093/nutrit/nuy047
Abstract: Studies in rats have shown that a decrease in either protein content or total dietary calories results in molecular, structural, and functional changes in the cerebral cortex and hippocampus, among other brain regions, which lead… read more here.
Keywords: fetal programming; brain; prenatal malnutrition; facts hypotheses ... See more keywords
Dose threshold for radiation induced fetal programming in a mouse model at 4 months of age: Hepatic expression of genes and proteins involved in glucose metabolism and glucose uptake in brown adipose tissue
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0231650
Abstract: Exposure to ionizing radiation contributing to negative health outcomes is a widespread concern. However, the impact of low dose and sub-lethal dose radiation (SLDR) exposures remain contentious, particularly in pregnant women who represent a vulnerable… read more here.
Keywords: fetal programming; glucose metabolism; expression; dose ... See more keywords
Hyperthyroidism in pregnancy: evidence and hypothesis in fetal programming and development
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine Connections"
DOI: 10.1530/ec-20-0518
Abstract: The management of hyperthyroidism in pregnant patients has been a topic of raised clinical awareness for decades. It is a strong recommendation that overt hyperthyroidism of Graves’ disease in pregnant women should be treated to… read more here.
Keywords: hyperthyroidism pregnancy; pregnancy; hyperthyroidism; fetal programming ... See more keywords
Fetal Programming by Methyl Donors Modulates Central Inflammation and Prevents Food Addiction-Like Behavior in Rats
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.00452
Abstract: Fetal programming by hypercaloric intake leads to food addiction-like behavior and brain pro-inflammatory gene expression in offspring. The role of methylome modulation during programming on central immune activation and addiction-like behavior has not been characterized.… read more here.
Keywords: addiction like; food addiction; like behavior; fetal programming ... See more keywords