Single-cell transcriptome analysis reveals the dynamics of human immune cells during early fetal skin development.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109524
Abstract: The immune system of skin develops in stages in mice. However, the developmental dynamics of immune cells in human skin remains elusive. Here, we perform transcriptome profiling of CD45+ hematopoietic cells in human fetal skin… read more here.
Keywords: single cell; skin; fetal skin; immune cells ... See more keywords
Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis
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DOI: 10.1371/journal.pone.0184938
Abstract: Background Intrauterine infection is a primary cause of preterm birth and fetal injury. The pro-inflammatory role of the fetal skin in the setting of intrauterine infection remains poorly characterized. Whether or not inflammation of the… read more here.
Keywords: fetal skin; pro inflammatory; inflammatory response; primate ... See more keywords
Human fetal skin derived merkel cells display distinctive characteristics in vitro and in bio-engineered skin substitutes in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.983870
Abstract: Human skin contains specialized neuroendocrine Merkel cells responsible for fine touch sensation. In the present study, we performed in-depth analysis of Merkel cells in human fetal back skin. We revealed that these Merkel cells expressed… read more here.
Keywords: merkel cells; skin; fetal skin; human fetal ... See more keywords