Enhanced thymocyte apoptosis induced by maternal undernutrition in late gestation results in declined mature T cells in rat fetal thymus.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2017.08.018
Abstract: This study was designed to observe the effects of maternal food restriction (MFR) on the development of fetal thymus in different gestation periods. Timed pregnant rats were randomized into 3 groups: CN (free access to… read more here.
Keywords: thymocyte apoptosis; gestation; enhanced thymocyte; fetal thymus ... See more keywords
Antenatal corticosteroid administration is associated with decreased growth of the fetal thymus: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Perinatology"
DOI: 10.1038/s41372-019-0554-z
Abstract: ObjectiveTo examine the effect of antenatal corticosteroid administration (ACS) on fetal thymus growth in women who received ACS compared with gestational-age-matched controls.Study designFetal thymus size and growth were measured in women at risk for preterm… read more here.
Keywords: corticosteroid administration; thymus; antenatal corticosteroid; fetal thymus ... See more keywords
High-Oxygen Submersion Fetal Thymus Organ Cultures Enable FOXN1-Dependent and -Independent Support of T Lymphopoiesis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.652665
Abstract: T cell development is effectively supported in fetal thymus organ cultures (FTOCs), which places thymus lobes atop an air-liquid interface (ALI) culture system. The direct exposure to air is critical for its success, as fetal… read more here.
Keywords: oxygen; expression; fetal thymus; oxygen submersion ... See more keywords