Alpha-fetoprotein mediated targeting of polymeric nanoparticles to treat solid tumors.
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DOI: 10.2217/nnm-2022-0097
Abstract: Background: Serious side effects caused by paclitaxel formulation, containing toxic solubilizer Cremophor® EL, and its nonspecific accumulation greatly limit clinical paclitaxel application. Aim: To design paclitaxel-loaded copolymer of lactic and glycolic acids nanoparticles decorated with alpha-fetoprotein third domain… read more here.
Keywords: targeting polymeric; mediated targeting; polymeric nanoparticles; fetoprotein mediated ... See more keywords