Study on the detoxification mechanisms to 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrinato iron(III) chloride (FeTPPS), an efficient pro-oxidant of heme water-soluble analogue.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2018.08.016
Abstract: 5,10,15,20-Tetrakis (4-sulfonatophenyl) porphyrinato iron(III) chloride (FeTPPS) is a water-soluble analog of heme and widely employed as peroxynitrite scavenger in vivo. However, previous studies have showed that like heme, FeTPPS could also act as an effective… read more here.
Keywords: porphyrinato iron; heme; sulfonatophenyl porphyrinato; iron iii ... See more keywords
FeTPPS Reduces Secondary Damage and Improves Neurobehavioral Functions after Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2017.00006
Abstract: Traumatic brain injury (TBI) determinate a cascade of events that rapidly lead to neuron's damage and death. We already reported that administration of FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possessed… read more here.
Keywords: traumatic brain; damage; tbi; injury ... See more keywords