Articles with "fetuin" as a keyword



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Evaluation of the effect of scaling and root planing on salivary and serum fetuin-A levels in patients with stages II-III periodontitis.

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Published in 2021 at "Journal of periodontology"

DOI: 10.1002/jper.21-0179

Abstract: BACKGROUND Fetuin-A has garnered colossal recognition in the etiopathogenesis of several systemic disorders. It has been recently acknowledged as an anti-inflammatory marker for periodontal disease. This study aimed to compare and correlate salivary and serum… read more here.

Keywords: serum fetuin; fetuin; fetuin levels; periodontitis ... See more keywords
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The association between circulating fetuin-A levels and type 2 diabetes mellitus risk: systematic review and meta-analysis of observational studies

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Published in 2017 at "Journal of Endocrinological Investigation"

DOI: 10.1007/s40618-017-0697-8

Abstract: Background and objectiveFetuin-A is a liver-derived circulating protein that is associated with insulin resistance and diabetes. The objective of this systematic review and meta-analysis of published observational studies was to investigate mean levels of fetuin-A… read more here.

Keywords: risk; review meta; systematic review; fetuin levels ... See more keywords
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Blocking TLR4-NF-κB pathway protects mouse islets from the combinatorial impact of high fat and fetuin-A mediated dysfunction and restores ability for insulin secretion

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Published in 2021 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2021.111314

Abstract: Lipid mediated pancreatic β-cell dysfunction during Type 2 diabetes is known to be regulated by activation of TLR4 (Toll Like Receptor 4) and NF-κB (Nuclear factor kappa B). Recently we have reported that MIN6 cells… read more here.

Keywords: secretion; insulin secretion; dysfunction; high fat ... See more keywords
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Maternal malnourishment induced upregulation of fetuin-B blunts nephrogenesis in the low birth weight neonate.

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Published in 2018 at "Developmental biology"

DOI: 10.1016/j.ydbio.2018.09.001

Abstract: Maternal undernutrition during pregnancy (MUN) often leads to low birth weight (LBW) neonates that have a reduced total nephron endowment, leaving these neonates susceptible to kidney disease throughout their lives. For reasons unknown, these LBW… read more here.

Keywords: low birth; six2 stem; birth weight; mun ... See more keywords
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Effects of fetuin-A-containing calciprotein particles on posttranslational modifications of fetuin-A in HepG2 cells

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-86881-0

Abstract: Fetuin-A is an inhibitor of ectopic calcification that is expressed mainly in hepatocytes and is secreted into the circulation after posttranslational processing, including glycosylation and phosphorylation. The molecular weight (MW) of fully modified fetuin-A (FM-fetuin-A)… read more here.

Keywords: secondary cpp; calciprotein particles; hepg2 cells; fetuin hepg2 ... See more keywords
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Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men

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Published in 2017 at "Journal of Diabetes Research"

DOI: 10.1155/2017/1492581

Abstract: Aerobic exercise training and weight loss (AEX+WL) improves insulin sensitivity in overweight adults; however, the underlying pathways are incompletely understood. Fetuin-A, a hepatokine that inhibits insulin signaling, may be involved in the salutary effects of… read more here.

Keywords: older men; plasma fetuin; fetuin levels; insulin sensitivity ... See more keywords
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Abstract P083: Fetuin-a Induces Vascular Dysfunction Through Toll-like Receptor 4 And Nox1/4 Activation

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Published in 2020 at "Hypertension"

DOI: 10.1161/hyp.76.suppl_1.p083

Abstract: Although studies demonstrate an important role for fetuin-A (FetA) in the inhibition of vascular calcification, convincing evidence suggests that fetuin-A is also involved in insulin resistance, inflammation and cardiovascular damage. The present study seeks to… read more here.

Keywords: like receptor; toll like; fetuin; vascular dysfunction ... See more keywords

Fetuin-A and risk of diabetes-related vascular complications: a prospective study

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Published in 2022 at "Cardiovascular Diabetology"

DOI: 10.1186/s12933-021-01439-8

Abstract: Background Fetuin-A is a hepatokine which has the capacity to prevent vascular calcification. Moreover, it is linked to the induction of metabolic dysfunction, insulin resistance and associated with increased risk of diabetes. It has not… read more here.

Keywords: risk; microvascular macrovascular; risk diabetes; plasma fetuin ... See more keywords
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Effects of exercise training on Fetuin-a in obese, type 2 diabetes and cardiovascular disease in adults and elderly: a systematic review and Meta-analysis

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Published in 2019 at "Lipids in Health and Disease"

DOI: 10.1186/s12944-019-0962-2

Abstract: BackgroundElevated levels of fetuin-A are associated with increased risks of metabolic syndrome, type 2 diabetes and nonalcoholic fatty liver disease. This meta-analysis investigated whether exercise interventions can reduce fetuin-A in adults.MethodsWe searched clinical trials that… read more here.

Keywords: analysis; disease; type diabetes; fetuin ... See more keywords

AMP activated kinase negatively regulates hepatic Fetuin-A via p38 MAPK-C/EBPβ/E3 Ubiquitin Ligase Signaling pathway

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0266472

Abstract: Fetuin-A (Fet-A) is a liver-secreted phosphorylated protein, known to impair insulin signaling, which has been shown to be associated with obesity, insulin resistance, and incident diabetes. Fet-A interacts with the insulin-stimulated insulin receptor (IR) and… read more here.

Keywords: fetuin; p38 mapk; fet expression; expression ... See more keywords
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Post-translational modifications glycosylation and phosphorylation of the major hepatic plasma protein fetuin-A are associated with CNS inflammation in children

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0268592

Abstract: Fetuin-A is a liver derived plasma protein showing highest serum concentrations in utero, preterm infants, and neonates. Fetuin-A is also present in cerebrospinal fluid (CSF). The origin of CSF fetuin-A, blood-derived via the blood-CSF barrier… read more here.

Keywords: inflammation; csf; fetuin; blood ... See more keywords