Free‐fatty acid receptor‐4 (FFA4) modulates ROS generation and COX‐2 expression via the C‐terminal &bgr;‐arrestin phosphosensor in Raw 264.7 macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.09.008
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Agonism of the G protein‐coupled free‐fatty acid receptor‐4 (FFA4) has been shown to promote numerous anti‐inflammatory effects in macrophages that arise due to interaction with &bgr;‐arrestin partner proteins.… read more here.
Keywords: bgr arrestin; ffa4; bgr; arrestin phosphosensor ... See more keywords
Free Fatty Acid Receptor 4 (FFA4) Activation Ameliorates Imiquimod-Induced Psoriasis in Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094482
Abstract: Dietary supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) has been used as an adjunct therapy for psoriasis due to its anti-inflammatory properties. Free fatty acid receptor 4 (FFA4 or GPR120) is a receptor-sensing n-3… read more here.
Keywords: ffa4; induced psoriasis; imiquimod induced; psoriasis ... See more keywords