VE-PTP inhibition stabilizes endothelial junctions by activating FGD5.
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DOI: 10.15252/embr.201847046
Abstract: Inhibition of VE-PTP, an endothelial receptor-type tyrosine phosphatase, triggers phosphorylation of the tyrosine kinase receptor Tie-2, which leads to the suppression of inflammation-induced vascular permeability. Analyzing the underlying mechanism, we show here that inhibition of… read more here.
Keywords: ptp inhibition; endothelial junctions; inhibition; fgd5 ... See more keywords