Articles with "fgf" as a keyword



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Effects of FGF‐23‐mediated ERK/MAPK signaling pathway on parathyroid hormone secretion of parathyroid cells in rats with secondary hyperparathyroidism

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Published in 2018 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.26525

Abstract: This study is supposed to investigate the effect of FGF‐23 on parathyroid hormone (PTH) secretion through ERK/MAPK signaling pathway in secondary hyperparathyroidism (SHPT) rat model. Thirty rats were equally served as the normal and SHPT… read more here.

Keywords: protein; fgf; secretion; parathyroid cells ... See more keywords
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Deficiency of fibroblast growth factor 2 (FGF‐2) leads to abnormal spermatogenesis and altered sperm physiology

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Published in 2018 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.26876

Abstract: In previous studies, we described the presence of fibroblast growth factor 2 (FGF‐2) and its receptors (FGFRs) in human testis and sperm, which are involved in spermatogenesis and in motility regulation. The aim of the… read more here.

Keywords: spermatogenesis; fgf; fibroblast growth; growth factor ... See more keywords
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Novel involvement of PLD–PKCδ–CREB axis in regulating FGF‐2‐mediated pentraxin 3 production in human nasal fibroblast cells

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Published in 2021 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.30657

Abstract: A higher expression level of mitogenic fibroblast growth factor‐2 (FGF‐2) has been reported in human nasal mucus of both chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Meanwhile, we have… read more here.

Keywords: creb; pkc creb; fgf; human nasal ... See more keywords
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FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK

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Published in 2020 at "Cellular and Molecular Life Sciences"

DOI: 10.1007/s00018-020-03630-8

Abstract: It is critical to specify a signal that directly drives the transition that occurs between cell states. However, such inferences are often confounded by indirect intercellular communications or secondary transcriptomic changes due to primary transcription… read more here.

Keywords: fgf; mek erk; braf mek; etv2 lmo2 ... See more keywords
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Fibroblast Growth Factor (FGF) 23 Regulates the Plasma Levels of Parathyroid Hormone In Vivo Through the FGF Receptor in Normocalcemia, But Not in Hypocalcemia

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Published in 2017 at "Calcified Tissue International"

DOI: 10.1007/s00223-017-0333-9

Abstract: The calcium and phosphate homeostasis is regulated by a complex interplay between parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), and calcitriol. Experimental studies have demonstrated an inhibitory effect of FG23 on PTH production and… read more here.

Keywords: pth; fgf; secretion; hypocalcemia ... See more keywords
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Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia

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Published in 2019 at "Obesity Surgery"

DOI: 10.1007/s11695-019-03845-0

Abstract: BackgroundHypoglycemia is an increasingly recognized complication of bariatric surgery. Mechanisms contributing to glucose lowering remain incompletely understood. We aimed to identify differentially abundant plasma proteins in patients with post-bariatric hypoglycemia (PBH) after Roux-en-Y gastric bypass… read more here.

Keywords: fgf; plasma; hypoglycemia; patients post ... See more keywords
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Low serm Fibroblast Growth Factor-21 levels is not associated with Carotid intima-media thickness in acromegaly patients

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Published in 2022 at "Journal of Endocrinological Investigation"

DOI: 10.1007/s40618-022-01775-w

Abstract: Elevated fibroblast growth factor-21 (FGF-21) levels are related to carotid intima-media thickness (CIMT), a well-established marker of atherosclerosis. Acromegaly has also been linked to increased CIMT. There has been no data considering the association between… read more here.

Keywords: growth factor; fgf levels; acromegaly patients; fgf ... See more keywords
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FGF-2 signaling activation in the hippocampus contributes to the behavioral and cellular responses to puerarin.

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Published in 2019 at "Biochemical pharmacology"

DOI: 10.1016/j.bcp.2019.06.025

Abstract: Puerarin, a well-studied isoflavone isolated from Pueraria lobata, produces an antidepressant-like effect. Fibroblast growth factor-2 (FGF-2) is essentially required in the central nervous system as it acts as both a neurotrophic or anti-inflammatory regulator for… read more here.

Keywords: fgf; hippocampus; puerarin; like effect ... See more keywords
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Novel culture system via wirelessly controllable optical stimulation of the FGF signaling pathway for human and pig pluripotency.

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Published in 2020 at "Biomaterials"

DOI: 10.1016/j.biomaterials.2020.120222

Abstract: Stem cell fate is largely determined by cellular signaling networks and is heavily dependent on the supplementation of exogenous recombinant proteins into culture media; however, uneven distribution and inconsistent stability of recombinant proteins are closely… read more here.

Keywords: fgf; controllable optical; fgf signaling; signaling pathway ... See more keywords
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Reply to letter to the editor: Elevated fibroblast growth factor-23 and risk for cardiovascular disease or mortality in the general population.

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Published in 2017 at "International journal of cardiology"

DOI: 10.1016/j.ijcard.2017.03.011

Abstract: We thank Krupp et al. for their insightful and well-thought comments on our article. We agree with them that there were some methodological flaws in our article. Studies on the association of elevated fibroblast growth… read more here.

Keywords: fgf; risk; fibroblast growth; elevated fibroblast ... See more keywords
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FGF-2 targets sclerostin in bone and myostatin in skeletal muscle to mitigate the deleterious effects of glucocorticoid on musculoskeletal degradation.

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Published in 2019 at "Life sciences"

DOI: 10.1016/j.lfs.2019.05.022

Abstract: AIM Myokines are associated with regulation of bone and muscle mass. However, limited information is available regarding the impact of myokines on glucocorticoid (GC) mediated adverse effects on the musculoskeletal system. This study investigates the… read more here.

Keywords: fgf; myostatin; skeletal muscle; muscle ... See more keywords