Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti-AChR Antibody-Positive Myasthenia Gravis: FGF-19 as a Novel Biomarker.
Sign Up to like & getrecommendations! Published in 2025 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.70261
Abstract: OBJECTIVE This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. METHODS We analyzed the… read more here.
Keywords: treatment; proteomics analysis; myasthenia gravis; efg treatment ... See more keywords
Effects of FGF‐23‐mediated ERK/MAPK signaling pathway on parathyroid hormone secretion of parathyroid cells in rats with secondary hyperparathyroidism
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26525
Abstract: This study is supposed to investigate the effect of FGF‐23 on parathyroid hormone (PTH) secretion through ERK/MAPK signaling pathway in secondary hyperparathyroidism (SHPT) rat model. Thirty rats were equally served as the normal and SHPT… read more here.
Keywords: protein; fgf; secretion; parathyroid cells ... See more keywords
Deficiency of fibroblast growth factor 2 (FGF‐2) leads to abnormal spermatogenesis and altered sperm physiology
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26876
Abstract: In previous studies, we described the presence of fibroblast growth factor 2 (FGF‐2) and its receptors (FGFRs) in human testis and sperm, which are involved in spermatogenesis and in motility regulation. The aim of the… read more here.
Keywords: spermatogenesis; fgf; fibroblast growth; growth factor ... See more keywords
Novel involvement of PLD–PKCδ–CREB axis in regulating FGF‐2‐mediated pentraxin 3 production in human nasal fibroblast cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30657
Abstract: A higher expression level of mitogenic fibroblast growth factor‐2 (FGF‐2) has been reported in human nasal mucus of both chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Meanwhile, we have… read more here.
Keywords: creb; pkc creb; fgf; human nasal ... See more keywords
FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-020-03630-8
Abstract: It is critical to specify a signal that directly drives the transition that occurs between cell states. However, such inferences are often confounded by indirect intercellular communications or secondary transcriptomic changes due to primary transcription… read more here.
Keywords: fgf; mek erk; braf mek; etv2 lmo2 ... See more keywords
Fibroblast Growth Factor (FGF) 23 Regulates the Plasma Levels of Parathyroid Hormone In Vivo Through the FGF Receptor in Normocalcemia, But Not in Hypocalcemia
Sign Up to like & getrecommendations! Published in 2017 at "Calcified Tissue International"
DOI: 10.1007/s00223-017-0333-9
Abstract: The calcium and phosphate homeostasis is regulated by a complex interplay between parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), and calcitriol. Experimental studies have demonstrated an inhibitory effect of FG23 on PTH production and… read more here.
Keywords: pth; fgf; secretion; hypocalcemia ... See more keywords
Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia
Sign Up to like & getrecommendations! Published in 2019 at "Obesity Surgery"
DOI: 10.1007/s11695-019-03845-0
Abstract: BackgroundHypoglycemia is an increasingly recognized complication of bariatric surgery. Mechanisms contributing to glucose lowering remain incompletely understood. We aimed to identify differentially abundant plasma proteins in patients with post-bariatric hypoglycemia (PBH) after Roux-en-Y gastric bypass… read more here.
Keywords: fgf; plasma; hypoglycemia; patients post ... See more keywords
Low serm Fibroblast Growth Factor-21 levels is not associated with Carotid intima-media thickness in acromegaly patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-022-01775-w
Abstract: Elevated fibroblast growth factor-21 (FGF-21) levels are related to carotid intima-media thickness (CIMT), a well-established marker of atherosclerosis. Acromegaly has also been linked to increased CIMT. There has been no data considering the association between… read more here.
Keywords: growth factor; fgf levels; acromegaly patients; fgf ... See more keywords
FGF-2 signaling activation in the hippocampus contributes to the behavioral and cellular responses to puerarin.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.06.025
Abstract: Puerarin, a well-studied isoflavone isolated from Pueraria lobata, produces an antidepressant-like effect. Fibroblast growth factor-2 (FGF-2) is essentially required in the central nervous system as it acts as both a neurotrophic or anti-inflammatory regulator for… read more here.
Keywords: fgf; hippocampus; puerarin; like effect ... See more keywords
Novel culture system via wirelessly controllable optical stimulation of the FGF signaling pathway for human and pig pluripotency.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120222
Abstract: Stem cell fate is largely determined by cellular signaling networks and is heavily dependent on the supplementation of exogenous recombinant proteins into culture media; however, uneven distribution and inconsistent stability of recombinant proteins are closely… read more here.
Keywords: fgf; controllable optical; fgf signaling; signaling pathway ... See more keywords
Reply to letter to the editor: Elevated fibroblast growth factor-23 and risk for cardiovascular disease or mortality in the general population.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2017.03.011
Abstract: We thank Krupp et al. for their insightful and well-thought comments on our article. We agree with them that there were some methodological flaws in our article. Studies on the association of elevated fibroblast growth… read more here.
Keywords: fgf; risk; fibroblast growth; elevated fibroblast ... See more keywords