The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone
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DOI: 10.1038/s41598-017-17888-9
Abstract: The mechanisms hallmarking melanoma progression are insufficiently understood. Here we studied the impact of the unfolded protein response (UPR) - a signalling cascade playing ambiguous roles in carcinogenesis - in melanoma malignancy. We identified isogenic… read more here.
Keywords: unfolded protein; protein response; fgf expression; expression ... See more keywords
The Role of Recombinant Secretory Leukocyte Protease Inhibitor to CD163, FGF-2, IL-1 and IL-6 Expression in Skin Wound Healing
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DOI: 10.2147/ccid.s358897
Abstract: Background The wound healing process can be optimized through the addition of a biomaterial such as recombinant secretory leukocyte protease inhibitor (rSLPI). The SLPI is a non-glycosylated proteomic material that inhibits protease enzymes and has… read more here.
Keywords: fgf expression; rslpi; wound healing; expression ... See more keywords