Generation and validation of novel conditional flox and inducible Cre alleles targeting fibroblast growth factor 18 (Fgf18)
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DOI: 10.1002/dvdy.85
Abstract: Fibroblast growth factor 18 (FGF18) functions in the development of several tissues, including the lung, limb bud, palate, skeleton, central nervous system, and hair follicle. Mice containing a germline knockout of Fgf18 (Fgf18 −/−) die… read more here.
Keywords: growth factor; factor fgf18; fibroblast growth; fgf18 ... See more keywords
Fibroblast growth factor 18 exerts anti‐osteoarthritic effects through PI3K‐AKT signaling and mitochondrial fusion and fission
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DOI: 10.1016/j.phrs.2018.09.026
Abstract: &NA; Osteoarthritis (OA) is a degenerative disease characterized by progressive loss of cartilage, osteophyte formation and subchondral bone sclerosis. Although some animal experiments have reported that fibroblast growth factor 18 (FGF18) attenuates cartilage degradation, the… read more here.
Keywords: akt signaling; fgf18; pi3k akt; mitochondrial fusion ... See more keywords