Analysis of FGF20‐regulated genes in organ of Corti progenitors by translating ribosome affinity purification
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DOI: 10.1002/dvdy.211
Abstract: Understanding the mechanisms that regulate hair cell (HC) differentiation in the organ of Corti (OC) is essential to designing genetic therapies for hearing loss due to HC loss or damage. We have previously identified Fibroblast… read more here.
Keywords: ribosome affinity; fgf20; organ corti; affinity purification ... See more keywords
Targeted repositioning identifies drugs that increase fibroblast growth factor 20 production and protect against 6-hydroxydopamine-induced nigral cell loss in rats
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-44803-1
Abstract: Endogenous fibroblast growth factor 20 (FGF20) supports maintenance of dopaminergic neurones within the nigrostriatal pathway. Moreover, direct intracerebral infusion of FGF20 protects against nigrostriatal tract loss in the 6-hydroxydopamine lesion rat model of Parkinson’s disease.… read more here.
Keywords: production; fgf20; targeted repositioning; fibroblast growth ... See more keywords