MS-275 induces hepatic FGF21 expression via H3K18ac-mediated CREBH signal.
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DOI: 10.1530/jme-18-0259
Abstract: Fibroblast growth factor 21(FGF21) plays an important role in the regulation of lipid and glucose metabolism. MS-275, as a class I-specific histone deacetylase (HDAC) inhibitor, has also been reported to affect energy metabolism. In this… read more here.
Keywords: hepatic fgf21; expression; h3k18ac; 275 induces ... See more keywords