In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
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DOI: 10.1038/s41467-020-18031-5
Abstract: Our understanding of the spatiotemporal regulation of cardiogenesis is hindered by the difficulties in modeling this complex organ currently by in vitro models. Here we develop a method to generate heart organoids from mouse embryonic… read more here.
Keywords: generation functional; fgf4; heart organoids; heart ... See more keywords
In-Silico Analysis of Deleterious SNPs of FGF4 Gene and Their Impacts on Protein Structure, Function and Bladder Cancer Prognosis
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DOI: 10.3390/life12071018
Abstract: Dysregulation of fibroblast growth factors is linked to the pathogenesis of bladder cancer. The role of FGF1 and FGF3 is evident in bladder cancer; however, the role of FGF4 is vague. Despite being reported that… read more here.
Keywords: fgf4; silico analysis; bladder cancer; bladder ... See more keywords