Articles with "fgfr1 fgfr3" as a keyword



Pemigatinib in previously treated solid tumors with activating FGFR1–FGFR3 alterations: phase 2 FIGHT-207 basket trial

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Published in 2024 at "Nature Medicine"

DOI: 10.1038/s41591-024-02934-7

Abstract: Fibroblast growth factor receptor (FGFR) alterations drive oncogenesis in multiple tumor types. Here we studied pemigatinib, a selective, potent, oral FGFR1–FGFR3 inhibitor, in the phase 2 FIGHT-207 basket study of FGFR-altered advanced solid tumors. Primary… read more here.

Keywords: response; fgfr1 fgfr3; basket; tumor types ... See more keywords