Small‐Molecule Inhibitors of the Tumor Suppressor Fhit
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DOI: 10.1002/cbic.201700226
Abstract: The tumor suppressor Fhit and its substrate diadenosine triphosphate (Ap3A) are important factors in cancer development and progression. Fhit has Ap3A hydrolase activity and cleaves Ap3A into adenosine monophosphate (AMP) and adenosine diphosphate (ADP); this… read more here.
Keywords: fhit; suppressor fhit; tumor suppressor; small molecule ... See more keywords